- Response of phytoplankton communities including harmful algal blooms to changing nutrient loads, physical and biological disturbances and climate change
- Prediction and development of hypoxia and anoxia in lakes depending on the external nutrient loadings, internal production and variability in climate
- Winter dynamics of phytoplankton and nutrients in large ice covered lakes
- The impact of mussels on water quality in lakes
Serghei’s broader research interest include coupling watershed and lake models to evaluate the short- and long-term impacts of changing climate and land-use on water quality in lakes to assess possible mitigation and adaptation strategies.