“Drugs in Lactation” Analysis Consortium (DLAC)
A new website has been created to aid in recruitment of breastfeeding mothers for the DLAC project (www.thedlac.com).
See the University of Waterloo, School of Pharmacy Facebook page (https://www.facebook.com/UWPharmacy/) to hear PhD candidate, Paul Malik, speak about his research using mathematical models to analyze how cancer drug concentrations change in the body over time in virtual children.
Dr. Pierre Chelle has joined the Edginton lab as a postdoctoral fellow.
Dr. Chelle recently completed his PhD at the Ecole Nationale Supérieure des Mines de Saint-Etienne, Saint-Etienne, France. The subject of his thesis was: Thrombin generation modeling in the framework of hemophilia treatment.
Dr. Edginton is a member of the “Drugs in Lactation” Analysis Consortium (DLAC). DLACis a network of scientists who explore drug safety during breastfeeding. The network is designed for collection of patient breast milk samples in a real world setting, to generate pharmacokinetic information (how drugs are absorbed, distributed in body and metabolized). This information enables the researchers to predict drug levels in human milk and infant blood in a population.
DLAC is headed by Dr. Shinya Ito and is housed at SickKids in Toronto, ON, Canada.
Dr. Anil Maharaj recently defended and has received the W.B. Pearson Medal from the Faculty of Science for recognition of creative research as presented in his Ph.D. thesis.
Dr. Maharaj was also awarded, based on the strength of his academic accomplishments, an “Outstanding Achievement in Graduate Studies” honour from the University of Waterloo.
Dr. Maharaj is currently a postdoctoral fellow at St. Jude Children's Research Hospital in Memphis, TN.
Alanna McEneny-King, a PhD student in Dr. Edginton's lab, has received a three-year CIHR Doctoral Award. She was ranked 3rd out of 479 applicants in her pool across Canada. This award is testament to the tenacity, intellect and creativity she has demonstrated during the past 1.5 years of her PhD. The Edginton lab congratulates Alanna on all of her accomplishments!
Dr. Edginton has joined the Board of Directors of the Centre for Bioengineering and Biotechnology (CBB) for a two year term starting January 2017. The Board of Directors is key to CBB's growth and the development of innovative research and research opportunities within industry and healthcare institutions both internationally and locally.
Anil Maharaj successfully completed his PhD thesis defense on February 28, 2017. The thesis was entitled:
Parameterization of in silico Oral Disposition Models: Focus on Pediatrics
CONGRATULATIONS ANIL!
Anil is now moving on to a postdoctoral fellowship at St. Jude's Children's Hospital in Memphis in the lab of Dr. Clinton Stewart.
MSc student Paul Malik (started September 2016) with former postdoctoral fellow Dr. Colin Phipps (applied mathematician; now at Abbvie) and visiting scientist, Dr. Abdullah Hamadeh (applied mathematician) recently published a manuscript on methods for understanding the mechanistic underpinnings of antibody PK interindividual variability.
Malik PR, Hamadeh A, Phipps C, Edginton AN. 2017. Population PBPK modelling of trastuzumab: a framework for quantifying and predicting interindividual variability. Journal of Pharmacokinetics and Pharmacodynamics. In press.
PhD candidate, Alanna McEneny-King, MSc, speaks at the 61st Annual meeting of the Society of Thrombosis and Hemostasis Research meeting in Basel, Switzerland, Feb 15-18, 2017. Her talk titled: Individual pharmacokinetic assessment - the WAPPS-Hemo Project will highlight the work that the Edginton lab is doing in conjunction with Alfonso Iorio MD (PI) at McMaster University on the Web-Accessible Population Pharmacokinetics Service - Hemophilia (https://www.wapps-hemo.org/).