Publications

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Author Title Type [ Year(Desc)]
2022
Layton, A. T. , & Sadria, M. . (2022). Understanding the dynamics of SARS-CoV-2 variants of concern in Ontario, Canada: a modeling study. Scientific Reports, 12, 2114. Nature Publishing Group UK London.
Stadt, M. M. , & Layton, A. T. . (2022). Adaptive changes in single-nephron GFR, tubular morphology, and transport in a pregnant rat nephron: modeling and analysis. American Journal of Physiology-Renal Physiology, 322, F121–F137. American Physiological Society Rockville, MD.
Leete, J. , Wang, C. , López-Hernández, F. J. , & Layton, A. T. . (2022). Determining risk factors for triple whammy acute kidney injury. Mathematical Biosciences, 347, 108809. Elsevier.
Sadria, M. , Seo, D. , & Layton, A. T. . (2022). The mixed blessing of AMPK signaling in Cancer treatments. BMC cancer, 22, 1–16. BioMed Central.
Swapnasrita, S. , Carlier, A. , & Layton, A. T. . (2022). Sex-specific computational models of kidney function in patients with diabetes. Frontiers in physiology, 13, 14. Frontiers.
2023
Hakimi, S. , Dutta, P. , & Layton, A. T. . (2023). Coupling of renal sodium and calcium transport: a modeling analysis of transporter inhibition and sex differences. American Journal of Physiology-Renal Physiology, 325, F536–F551. American Physiological Society Rockville, MD.
Layton, A. T. , & Vallon, V. . (2023). Did you know how SGLT2 inhibitors protect the kidney?. Acta Physiologica, e14011.
Layton, A. T. . (2023). “Hi, how can i help you?”: embracing artificial intelligence in kidney research. American Journal of Physiology-Renal Physiology, 325, F395–F406. American Physiological Society Rockville, MD.
Smith, D. , & Layton, A. . (2023). Impact of angiotensin-receptor blockers on intrarenal renin-angiotensin system activity in hypertension: A PK/PD modelling study. bioRxiv, 2023–07. Cold Spring Harbor Laboratory.
Saulnier, P. J. , Looker, H. C. , Layton, A. , Lemley, K. V. , Nelson, R. G. , & Bjornstad, P. . (2023). Loss of Glomerular Permselectivity in Type 2 Diabetes Associates with Progression to Kidney Failure. Diabetes, 72, 1682–1691. American Diabetes Association.
Stadt, M. M. , & Layton, A. T. . (2023). Mathematical modeling of calcium homeostasis in female rats: An analysis of sex differences and maternal adaptations. Journal of Theoretical Biology, 572, 111583. Academic Press.
Dutta, P. , & Layton, A. . (2023). Modeling magnesium and calcium transport along male rat kidney and the effects of diuretics. bioRxiv, 2023–10. Cold Spring Harbor Laboratory.
McDonough, A. A. , Layton, , & T., A. . (2023). Sex differences in renal electrolyte transport. Current Opinion in Nephrology and Hypertension, 10, 1097.
McDonough, A. A. , Harris, A. N. , Xiong, L. , & Layton, A. T. . (2023). Sex differences in renal transporters: assessment and functional consequences. Nature Reviews Nephrology, 1–16. Nature Publishing Group UK London.
Sadria, M. , Layton, A. , & Bader, G. . (2023). Adversarial training improves model interpretability in single-cell RNA-seq analysis. bioRxiv, 2023–05. Cold Spring Harbor Laboratory.
Hakimi, S. , Dutta, P. , & Layton, A. . (2023). Coupling of renal sodium and calcium transport: A modeling analysis. bioRxiv, 2023–05. Cold Spring Harbor Laboratory.
Stadt, M. , Alexander, T. , & Layton, A. . (2023). Differential impacts of pregnancy and lactation on maternal calcium homeostasis: a mathematical modeling analysis. Physiology, 38, 5730988. American Physiological Society Rockville, MD.
Dutta, P. , Sadria, M. , & Layton, A. T. . (2023). Influence of administration time and sex on natriuretic, diuretic, and kaliuretic effects of diuretics. American Journal of Physiology-Renal Physiology, 324, F274–F286. American Physiological Society Rockville, MD.
Sadria, M. , Bjornstad, P. , Pottumarthi, P. , Lu-Ping, L. , Pyle, L. , Vigers, T. , & Layton, A. . (2023). A multimodal neural network that distinguishes between type 1 and type 2 diabetes in young persons using MRI and clinical data. Physiology, 38, 5695980. American Physiological Society Rockville, MD.
Sadria, M. , & Layton, A. . (2023). The Power of Two: integrating deep diffusion models and variational autoencoders for single-cell transcriptomics analysis. bioRxiv, 2023–04. Cold Spring Harbor Laboratory.

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