Publications

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Smith, D. , & Layton, A. . (2023). Impact of angiotensin-receptor blockers on intrarenal renin-angiotensin system activity in hypertension: A PK/PD modelling study. bioRxiv, 2023–07. Cold Spring Harbor Laboratory.
Smith, D. , & Layton, A. . (2023). The intrarenal renin-angiotensin system in hypertension: insights from mathematical modelling. Journal of Mathematical Biology, 86, 58. Springer Berlin Heidelberg Berlin/Heidelberg.
Smith, D. , & Layton, A. . (2022). Intrarenal Renin-Angiotensin System and its Role in Angiotensin II-Induced Hypertension: Insights from Computational Modelling. The FASEB Journal, 36. The Federation of American Societies for Experimental Biology.
Sgouralis, I. , & Layton, A. T. . (2017). Modeling blood flow and oxygenation in a diabetic rat kidney. In Women in Mathematical Biology: Research Collaboration Workshop, NIMBioS, Knoxville, June 2015 (pp. 101–113). Springer International Publishing.
Sgouralis, I. , Evans, R. G. , & Layton, A. T. . (2017). Renal medullary and urinary oxygen tension during cardiopulmonary bypass in the rat. Mathematical medicine and biology: a journal of the IMA, 34, 313–333. Oxford University Press.
Sgouralis, I. , & Layton, A. . (2016). Internephron Coupling Increases the Efficiency of Dynamic Autoregulation. The FASEB Journal, 30, 739–6. The Federation of American Societies for Experimental Biology.
Sgouralis, I. , Kett, M. M. , Ow, C. P. C. , Abdelkader, A. , Layton, A. T. , Gardiner, B. S. , Smith, D. W. , et al. (2016). Bladder urine oxygen tension for assessing renal medullary oxygenation in rabbits: experimental and modeling studies. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 311, R532–R544. American Physiological Society Bethesda, MD.
Sgouralis, I. , Maroulas, V. , & Layton, A. T. . (2016). Transfer function analysis of dynamic blood flow control in the rat kidney. Bulletin of mathematical biology, 78, 923–960. Springer US.
Sgouralis, I. , & Layton, A. T. . (2016). Conduction of feedback-mediated signal in a computational model of coupled nephrons. Mathematical Medicine and Biology: a Journal of the IMA, 33, 87–106. Oxford University Press.
Sgouralis, I. , Evans, R. , Gardiner, B. , & Layton, A. . (2015). Urinary PO2 as a biomarker for medullary hypoxia. The FASEB Journal, 29, 963–6. The Federation of American Societies for Experimental Biology.
Sgouralis, I. , & Layton, A. T. . (2015). Mathematical modeling of renal hemodynamics in physiology and pathophysiology. Mathematical biosciences, 264, 8–20. Elsevier.
Sgouralis, I. , Evans, R. G. , Gardiner, B. S. , Smith, J. A. , Fry, B. C. , & Layton, A. T. . (2015). Renal hemodynamics, function, and oxygenation during cardiac surgery performed on cardiopulmonary bypass: a modeling study. Physiological reports, 3, e12260.
Sgouralis, I. , Evans, R. , Gardiner, B. , & Layton, A. . (2014). Contribution of hemodilution to renal hypoxia following cardiopulmonary bypass surgery (890.12). The FASEB Journal, 28, 890–12. The Federation of American Societies for Experimental Biology.
Sgouralis, I. , & Layton, A. T. . (2014). Theoretical assessment of renal autoregulatory mechanisms. American Journal of Physiology-Renal Physiology, 306, F1357–F1371. American Physiological Society Bethesda, MD.
Sgouralis, I. , & Layton, A. . (2013). Nephrovascular interactions in a mathematical model of rat renal autoregulation. The Federation of American Societies for Experimental Biology.
Sgouralis, I. , & Layton, A. T. . (2013). Control and modulation of fluid flow in the rat kidney. Bulletin of mathematical biology, 75, 2551–2574. Springer US.
Sgouralis, I. , & Layton, A. T. . (2012). Interactions between Tubuloglomerular Feedback and the Myogenic Mechanism of the Afferent Arteriole. Federation of American Societies for Experimental Biology.
Sgouralis, I. , & Layton, A. T. . (2012). Autoregulation and conduction of vasomotor responses in a mathematical model of the rat afferent arteriole. American Journal of Physiology-Renal Physiology, 303, F229–F239. American Physiological Society Bethesda, MD.
Savage, N. S. , Layton, A. T. , & Lew, D. J. . (2012). Mechanistic mathematical model of polarity in yeast. Molecular biology of the cell, 23, 1998–2013. The American Society for Cell Biology.
Saulnier, P. J. , Looker, H. C. , Layton, A. , Lemley, K. V. , Nelson, R. G. , & Bjornstad, P. . (2023). Loss of Glomerular Permselectivity in Type 2 Diabetes Associates with Progression to Kidney Failure. Diabetes, 72, 1682–1691. American Diabetes Association.

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