Publications

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Author Title [ Type(Desc)] Year
Journal Article
Leete, J. , Gurley, S. , & Layton, A. T. . (2018). Modeling sex differences in the renin angiotensin system and the efficacy of antihypertensive therapies. Computers & chemical engineering, 112, 253–264. Pergamon.
Wei, N. , Gumz, M. L. , & Layton, A. T. . (2018). Predicted effect of circadian clock modulation of NHE3 of a proximal tubule cell on sodium transport. American Journal of Physiology-Renal Physiology, 315, F665–F676. American Physiological Society Bethesda, MD.
Layton, A. T. , & Vallon, V. . (2018). SGLT2 inhibition in a kidney with reduced nephron number: modeling and analysis of solute transport and metabolism. American Journal of Physiology-Renal Physiology, 314, F969–F984. American Physiological Society Bethesda, MD.
Wei, N. , & Layton, A. T. . (2018). Theoretical assessment of the Ca 2+ oscillations in the afferent arteriole smooth muscle cell of the rat kidney. International Journal of Biomathematics, 11, 1850043. World Scientific Publishing Company.
Layton, A. T. , & Edwards, A. . (2017). Introduction to Mathematical Modeling of Blood Flow Control in the Kidney. Women in Mathematical Biology, 63–73. Springer, Cham.
Burt, T. , Noveck, R. J. , MacLeod, D. B. , Layton, A. T. , Rowland, M. , & Lappin, G. . (2017). Intra-Target Microdosing (ITM): a novel drug development approach aimed at enabling safer and earlier translation of biological insights into human testing. Clinical and translational science, 10, 337. Wiley-Blackwell.
Layton, A. , Edwards, A. , & Vallon, V. . (2017). Modeling the Effects of Functional Adaptation to Reduction in Renal Mass. The FASEB Journal, 31, 716–2. The Federation of American Societies for Experimental Biology.
Sgouralis, I. , Evans, R. G. , & Layton, A. T. . (2017). Renal medullary and urinary oxygen tension during cardiopulmonary bypass in the rat. Mathematical medicine and biology: a journal of the IMA, 34, 313–333. Oxford University Press.
Edwards, A. , & Layton, A. T. . (2017). Cell volume regulation in the proximal tubule of rat kidney. Bulletin of mathematical biology, 79, 2512–2533. Springer US.
Layton, A. T. , Edwards, A. , & Vallon, V. . (2017). Renal potassium handling in rats with subtotal nephrectomy: modeling and analysis. American Journal of Physiology-Renal Physiology, 314, F643–F657. American Physiological Society Bethesda, MD.
Layton, A. T. . (2017). Sweet success? SGLT2 inhibitors and diabetes. American Journal of Physiology-Renal Physiology, 314, F1034–F1035. American Physiological Society Bethesda, MD.
Layton, A. T. , Pannabecker, T. L. , Dantzler, W. H. , & Layton, H. E. . (2017). Two modes for concentrating urine in rat inner medulla (vol 287, pg F816, 2004). AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 313, F1178–F1178. AMER PHYSIOLOGICAL SOC 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 USA.
Jiang, T. , Li, Y. , Layton, A. T. , Wang, W. , Sun, Y. , Li, M. , Zhou, H. , et al. (2017). Generation and phenotypic analysis of mice lacking all urea transporters. Kidney international, 91, 338–351. Elsevier.
Chen, Y. , Sullivan, J. C. , Edwards, A. , & Layton, A. T. . (2017). Sex-specific computational models of the spontaneously hypertensive rat kidneys: factors affecting nitric oxide bioavailability. American Journal of Physiology-Renal Physiology, 313, F174–F183. American Physiological Society Bethesda, MD.
Burt, T. , Noveck, R. J. , MacLeod, D. B. , Layton, A. T. , Rowland, M. , & Lappin, G. . (2017). Intra-Target Microdosing (ITM): a novel drug development approach aimed at enabling safer and earlier translation of biological insights into human testing. Clinical and translational science, 10, 337. Wiley-Blackwell.
Chen, Y. , Fry, B. C. , & Layton, A. T. . (2017). Modeling glucose metabolism and lactate production in the kidney. Mathematical biosciences, 289, 116–129. Elsevier.
Layton, A. T. . (2017). A new microscope for the kidney: mathematics. American Journal of Physiology-Renal Physiology, 312, F671–F672. American Physiological Society Bethesda, MD.
Layton, A. T. , Edwards, A. , & Vallon, V. . (2017). Adaptive changes in GFR, tubular morphology, and transport in subtotal nephrectomized kidneys: modeling and analysis. American Journal of Physiology-Renal Physiology, 313, F199–F209. American Physiological Society Bethesda, MD.
Layton, A. , Edwards, A. , & Vallon, V. . (2017). Modeling the Effects of Functional Adaptation to Reduction in Renal Mass. The FASEB Journal, 31, 716–2. The Federation of American Societies for Experimental Biology.
Layton, A. , Vallon, V. , & Edwards, A. . (2016). Effect of SGLT Inhibition on Medullary Oxygen Consumption: A Multi-Nephron Model of the Rat Kidney. The FASEB Journal, 30, 740–2. The Federation of American Societies for Experimental Biology.

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