Cohen JN, Hedge ET, Greaves DK, Robertson AD, Nahas H, Yu ACH, Petersen LG, Au JS. Characterization of internal jugular vein region-specific distension and flow patterns during progressive volume shifting. J Appl Physiol 2024, 137(1):32-41.
- This work explored how the internal jugular vein conforms to fluid shifts and used next-generation ultrasound imaging to detail what happens to blood when fluid shifts towards the head. This work is related to the previously noted risk of thromboembolism in astronauts during long-duration spaceflight.
- This work was done as part of Jeremy Cohen's PhD thesis.
Al-Bakry D, Athaide CE, Pathmarajan R, Kuhn T, Middleton L, Au JS. Short-term vascular responses to spring and fall daylight savings time shifts. Am J Physiol Heart Circ Physiol 2024, 326(5):H1138-H1145.
- This short report examined whether there are short-term changes to arterial health during the transition into and out of Daylight Savings Time in Canada. This is one of the only human studies to measure how the body responds to a societal schedule shift.
- This work was done as part of Dara Al-Bakry's senior undergraduate thesis.
Athaide CE*, Robertson AD, Devries MC, Au JS. Seated elliptical exercise, but not periodic standing, alleviates sitting-induced changes to arterial wave reflections. Med Sci Sports Exerc 2024, 56(5):953-962.
- This study examined what happens to the vascular system after a period of prolonged sitting and how exercise or standing countermeasures can alleviate some of the cardiovascular burden during periods of sedentary behaviour.
- This work was done as part of Chloe Athaide's MSc thesis.
Bryans CG*, Gopaul J*, Athaide CE*, Pugh CJA, Au JS. The influence of activity and sex on carotid artery longitudinal wall motion. Appl Physiol Nutr Metab 2024, 49(3):385-394.
- This cross-sectional study evaluated whether following the Canadian Physical Activity Guidelines is associated with more positive health of the carotid arteries. This study was conducted shortly after alleviation of COVID-19 related research pauses.
- This work was done as part of Carol Bryans' senior undergraduate thesis.
Cohen JN, Samra R, Au JS. Evidence for an 'arterial pump' venous return mechanism in humans. J Appl Physiol 2023, 56(4):673-681.
- This short report explored a potential new venous mechanism that helps blood return from the periphery back towards the heart. The central idea is that arteries that run parallel to greater veins help push blood on each pulsation. The effect is theorized to only occur when venous valves are active.
- This work was done as part of Jeremy Cohen's PhD thesis.
Athaide CE, Cohen JN, Stevens KA, Robertson AD, Au JS. Heating-induced peripheral limb microvascular vasodilation reduces arterial wave reflection. J Appl Physiol 2023, 134(5):1232-1239.
- This original article sought to investigate where arterial wave reflections originate in humans. As opposed to previous thinking that the muscular legs are quite important, we didn't show any differences between vasodilating the arm vs the leg to decrease wave reflection. Peripheral vasodilation seems to be important, but not the investigated limb, as per our results.
- This work was done as part of Chloe Athaide's MSc thesis.
Athaide CE, Samuel M, Jutlah LBL, Bryans CG, Au JS. The influence of respiration, neck flexion, and arterial segment on carotid artery longitudinal wall motion. J Appl Physiol 2023, 134(2):288-295.
- This methods paper identifies how the respiratory cycle, tilting the neck, and scanning location can impact the measured longitudinal wall motion curve in humans. The results of this study will establish guidelines for how to record longitudinal wall motion in humans.
- This work was done as part of Chloe Athaide's MSc independent study.
Hao Z, Rahman M, Jutlah LBL, Athaide CE, Au JS. Axial wall displacement at the common carotid artery is associated with the Lamb waves. J Eng Sci Med Diagn Ther 2023, 6(1):011008.
- This modelling paper investigates the contribution of longitudinally-moving Lamb's waves to the longitudinal wall motion waveform, as opposed to traditional Young's waves that propogate outwards.
- This work was done in collaboration with partners from Old Dominion University (Norfolk, VA, USA).
Athaide CE Spronck B, Au JS. Physiological basis for longitudinal motion of the arterial wall. Am J Physiol Heart Circ Physiol 2022, 322(5):H689-H701.
- This review summarizes the most up-to-date information on the physiology and regulation of carotid artery longitudinal wall motion.
- This work was done as part of Chloe Athaide's MSc independent study.
Stevens KA, Au JS. 2021. Case Studies in Physiology: Using premature ventricular contractions to understand the regulation of carotid artery longitudinal wall motion. J Appl Physiol, 131:1157-1161.
- This study examined how the heart, pulse, and arteries respond to a common type of arrythmia in a healthy male. Pre-mature ventricular contracts are 'extra beats' that occur when the left ventricle contracts before electrical activity arrives from the left atrial. This unique situation results in work of the left ventricle without actually ejecting much blood into the body.
- Forwards arterial wall motion remained unchanged despite large deviations in local blood velocity and backwards wall motion mirrored changes in pulse pressure, blood velocity, and cardiac motion, thereby revising our original hypothesis of the control of longitudinal wall motion.
- This work was done as part of Kailey Steven's undergraduate independent study.