Chris Eliasmith, Director of the Centre for Theoretical Neuroscience, received the prestigious John C. Polanyi Award and is also an inaugural member of the Royal Society of Canada's College of New Scholars, Artists, and Scientists.
Here is a list of our speakers for the 2016 and 2017 academic year:
October 18, 2016 - Robert Jacobs
December 1, 2016 - Noah Cowan
December 6, 2016 - Julio Martinez-Trujillo
February 29, 2017 - Richard Staines
March 13, 2017 - Ed Connor
March 28, 2017 - Gunnar Blohm
April 5, 2017 - Waterloo Brain Day (11th annual)
Tuesday, October 18, 2016
3:30 p.m. - 5:00 p.m.
University of Rochester
From Sensation to Conception: Theoretical Perspectives on Multisensory Perception and Cross-Modal Transfer
If a person is trained to recognize or categorize objects or events using one sensory modality, the person can often recognize or categorize those same (or similar) objects and events via a novel modality, an instance of cross-modal transfer of knowledge. How is this accomplished? The Multisensory Hypothesis states that people extract the intrinsic, modality-independent properties of objects and events, and represent these properties in mulitsensory representations. These representations mediate the transfer of knowledge across modality-specific representations. In this talk, I'll present two projects evaluating the Multisensory Hypothesis using experimental and computational methodologies. The first project examines visual-haptic transfer of object shape knowledge, and the second project examines a novel hidden (latent) variable model of multisensory perception. I'll also consider implications of an experiment demonstrating generalization from perception to motor production for our understanding of cross-modal transfer.
Department of Mechanical Engineering
John Hopkins University
Stabilizing the Unstable Brain
The nervous system may be the most sophisticated control system in the known universe, riding at the helm of an equally sophisticated plant. Understanding how the nervous system encodes and processes sensory information, and then computes motor action, therefore, involves understanding a closed loop. However it is often necessary to "isolate" all or part of the nervous system to study it. But there is no guarantee that the brain is "open-loop stable" and in fact there is good reason to believe that it is not. Here we discuss two problems in which we first close a feedback loop around the brain, and then take steps to perform system identification of the stabilized brain in order to understand its computations.
Mechanisms of Working Memory Coding in the Primate Brain: From Single Neurons to Neuronal Ensembles
Working memory is the ability to maintain and manipulate information that is not available to the senses during short time intervals. It is currently thought that working memory arises from the sustained activity of neurons selective for spatial locations, features, and complex objects in different areas of the primate brain. One issue that has been a matter of debate is what is the role of different brain areas in working memory coding. I will present data from electrophysiological recordings along the primate visual dorsal pathway during working memory tasks and compare the fidelity of working memory representations of spatial locations and features by single neurons amongst these areas. I will then focus on the prefrontal cortex and elaborate on how interactions between neurons shape the coding of working memory within this area, and how measurements of correlated activity can reveal important aspects of the dynamics underlying working memory coding. I will finally elaborate on the implications of these different findings for current models of working memory.
Department of Kinesiology
University of Waterloo
Crossmodal Influences in Somatosensory Cortex: Interaction of Vision, Touch, and Attention
Bimodal interactions between relevant visual and tactile inputs can facilitate attentional modulation at early stages in somatosensory cortices to achieve goal-oriented behaviors. However, the specific contribution of each sensory system during attentional processing and, importantly, how these interact with the required behavioural motor goals remains unclear. Experiments will be presented that used EEG and event-related potentials (ERPs) to test hypotheses that activity from modality-specific somatosensory cortical regions would be enhanced with task-relevant bimodal (visual-tactile) stimuli and suppressed when the same stimuli were in conflict for the behavioural task. Results show that specific modality-specific somatosensory ERPs are modulated with attentional state (either enhanced or suppressed) and this is related to the behavioural impacts when presented in conflict. Transient inhibition of the dorsolateral prefrontal cortex using transcranial magnetic stimulation reduces these attention-based modulations of tactile ERPs. The functional significance of this to sensorimotor behavior will be discussed.
Director, The Zanvyl Krieger Mind/Brain Institute
Johns Hopkins University
Shape Information in the Primate Brain
We study neural coding of shape in the ventral pathway of primate visual cortex. Because natural shape is a virtually infinite domain, neural coding is sparse and difficult to define. To compensate, we use genetic algorithms to focus stimulus sampling on the response ranges of specific neurons. This yields datasets that can constrain quantitative models relating stimulus geometry to neural responses. In previous studies, we have used genetic algorithms to show how objects are encoded as configurations of 3D surface fragments and medial axis elements. In recent work, we have studied large scale shape coding of scenes and rooms in the ventral pathway. In both object and scene representation, neural coding dimensions reflect the geometry of the natural world and the information we need about it.
Centre for Neuroscience Studies
Spiking Networks for Decision Making and Working Memory
Decision making and working memory are central to cognition. Working memory is the transient retention and manipulation of information that can then be used to make a selection among choices, i.e. a decision. I propose a unifying framework of neural dynamics that could underlie different key features of decision making (such as the speed-accuracy trade-off) and working memory (such as capacity, distractibility and overload). We developed spiking neural models that capture decisions and working memory independently or within the same network as a function of a single (cognitive) control parameter, which we propose to be distal network disinhibition. The predicted neural mechanisms are helpful in understanding canonical computations underlying a variety of cognitive process beyond decisions and working memory.