Engineering a faster future for genetic testing
Nanotechnology Engineering (NE) Group 22 placed second for their Capstone Design Project titled Detecting Mutations in Genes: A Microfluidic Lab-on-a-Chip Solution.
The group designed a benchtop microfluidic device which detects DNA mutations. DNA mutation detection can be used to tailor cancer treatments, identify genetic disorders like cystic fibrosis, prenatal testing and more.
DNA mutation detection is a time-consuming process. It takes between four to six hours to get the results from the current process of testing. The device designed by group members Gabriel Ghrayeb, Declan Gunning, Cyrus Hatami, and Alek Kechichian takes a small DNA sample and can process and produce results quickly and with minimal manual intervention.
“Our device works with and can be tuned for any DNA segment of interest, whether you're working in genetic engineering and you want to check if you have successfully caused or edited a gene mutation, or in genetic screening where we want to check if a person's genetic code has a mutation that might make them at higher risk for breast cancer or some other condition down the line,” says Kechichian.