Chiral pharmaceutical research featured on the cover of Analyst
Many pharmaceuticals and drugs of abuse released from wastewater treatment plants are chiral compounds. As our research expanded to include drugs of abuse in wastewater, we identified a unique analytical challenge: the enantiomers of tramadol and O-desmethylvenlafaxine overlap and cannot be adequately separated using conventional approaches. In collaboration with the Hopkins Lab in Chemistry at the University of Waterloo, a new two-dimensional chiral LC × DMS mass spectrometry method was developed to successfully separate and analyze these compounds. This collaborative work was featured on the cover of Analyst.