A recent article in Influents (Water Environment Association of Ontario) describes the recent work to model estrogens in the Grand River.
Arlos, M., W. Parker, S. Andrews, M. Servos. 2017. Relationship between estrogens and intersex in a major Lake Erie tributary: a modelling approach. Influents: Official Publication of the Water Environment Association of Ontario. Summer 2017: 52-55. http://www.kelmanonline.com/httpdocs/files/WEAO/influentssummer2017/index.html