Co-supervisors: Xu Zhang, Cape Breton University; Runquin Jiang, Grand River Hospital
Research Interests
In collaboration with Dr. Runqing Jiang of the Grand River Hospital, and Dr. Xu (Shine) Zhang of Cape Breton University, Brian’s research aims to develop a simple, multifunctional nanomaterial for the treatment of human prostate cancer in the form of gold nanoparticle-coated liposomes. Strong interactions between gold and clinical X-Rays, and the enhanced cancer permeability and retention of liposomes makes this platform a superior alternative to current CT contrast agents and allows for a focused enhancement of traditional radiation therapy. The unique physical structure of the gold-coated liposomes also enables the utilization of a localized surface plasmon resonance for experimental photothermal therapies and the triggered release of chemotherapeutics and other nanoparticles.
