Xu (Shine) Zhang, PhD

CIHR PDF (Alumni)

Shine is now a Research Fellow at the Cape Breton University.

Supervisors

Dr. Mark Servos [Department of Biology]

Dr. J. Liu [Waterloo Institute For Nanotechnology]

Research interests

My research focuses on developing and applying novel technologies for biomedical, pharmaceutical, and toxicological research, including

  1. In vivo extraction of pharmaceuticals in living fish;
  2. TiO2 (titanium dioxide) nanowire membrane for removal of emerging contaminants from water;
  3. Gold nanoparticles for biosensing and gene delivery;
  4. Microfluidic techniques for drug delivery;
  5. Nanotoxicity

Selected Publications

Click here to view all of Shine's publications

  1. Zhang, X., Oakes, K., Hoque, M., Luong, D., Metcalfe, C. D., Servos, M. R. (2012) Depth-Profiling of Environment Pharmaceuticals in Biological Tissue by Solid-Phase Microextraction. Analytical Chemistry, DOI: 10.1021/ac3004659. 84, 6956-6962.
  2. Zhang, X., Servos, M. R. Liu, J. (2012) Ultrahigh Nanoparticle Stability against Salt, pH and Solvent with Retained Surface Accessibility via Depletion Stabilization, Journal of the American Chemical Society, DOI: 10.1021/ja303787e. 134, 9910-9913.
  3. Zhang, X., Servos, M. R. Liu, J. (2012) Instantaneous and Quantitative Functionalization of Gold Nanoparticles with Thiolated DNA Using a pH-Assisted and Surfactant-Free Route, Journal of the American Chemical Society, DOI: 10.1021/ja3014055. 134, 7266– 7269.
  4. Zhang, X., Servos, M. R. Liu, J. (2012) The Surface Science of DNA Adsorption onto Citrate-Capped Gold Nanoparticles", Langmuir, DOI: 10.1021/la205036p. 28, 3896–3902.
  5. Zhang, X., Oakes, K., Hoque, M., Luong, D., Metcalfe, C. D., Servos, M. R. (2011) Solid-Phase Microextraction Coupled to LC-ESI-MS/MS: Evaluation and Correction for Matrix Effects for Pharmaceutical Analysis in Biological and Environmental Samples. Analytical Chemistry. 83, 6532–6538.
  6. Zhang, X., Oakes, K., Cui, S., Bragg, L., Servos, M., Pawliszyn, J. (2010) Tissue-specific In Vivo Bioaccumulation of Pharmaceuticals in Rainbow Trout (Oncorhynchus mykiss) using Space-resolved Solid-Phase Microextraction. Environmental Science &. Technology. 44, 3417-3422.

Shine Xu Zhang