Exploration and exploitation of microbes
The Waterloo Centre for Microbial Research (WCMR) promotes research and education in the application of microbiological principles and techniques to address environmental, industrial, economic, and human health challenges.
Through the WCMR, members with diverse research interests and varying academic backgrounds come together to engage in collaborative research in which microbes, as part of aquatic, terrestrial, engineered and host-associated environments, are explored through:
- computational analysis of sequence data
- identification of constituent species
- annotation and identification of novel molecular activities
- development of synthetic biology applications
- engineering of microbial processes for industrial applications
- participation in international sharing
- standardization of big data
- understanding the role of microbes in society.
As a group, the Waterloo Centre for Microbial Research plans to unify, catalyze, and promote multidisciplinary research which explores and exploits microbes at the University of Waterloo. The WCMR also supports partnerships between students, researchers, and external partners through networking events, collaborative projects and science communication. As of 2017, the WCMR is an official centre of the University of Waterloo.
News
SynBio8.0
WCMR will host SynBio8.0 June 15-17, 2026 in the Pearl Sullivan Engineering Building (E7)
To register, to learn more about accommodations and to submit your research paper, please visit SynBio8.0. Abstract deadline is March 31, 2026.
Please let us know if you are interested in volunteering at the event.
WCMR Director Announcement
New Waterloo Centre for Microbial Research Director Announcement
Events
SynBio8.0 - June 15-17, 2026
WCMR will host SynBio8.0 June 15-17, 2026 in the Pearl Sullivan Engineering Building (E7)
To register, learn more about accommodations and find out how to submit your research paper, please visit SynBio8.0.
Please let us know if you are interested in volunteering at the event.
2nd Annual WCMR Research Symposium
The 2026 WCMR Research Symposium event will take place on July 7. Details are being finalized, and a registration page will be available as soon as possible. Thank you!
WCMR Research Talk: Prof. David Stewart, University of Alberta
Tuesday July 7, 2026
1:30 pm
DC 1302
"Engineering microbial cells for application as live cell therapeutics"
The ominous rise in the frequency of antibiotic resistant microbial infections poses a global threat to human health. This threat comes in the direct form of disease related to infection of humans but also indirectly in the form of challenges to food security through loss of agricultural crops and animals to disease. The development of antibiotic drugs in previous decades was transformational, providing cheap, effective treatment for what would otherwise would be a lethal infection. As microbial strains resistant to our front-line antibiotic drugs have emerged, there is an urgent need to develop new therapeutic strategies and tools. Synthetic biology and metabolic engineering can be applied to generate "weaponized" live cell therapeutics providing new means to combat the rapidly evolving threat of microbial pathogens. In this presentation, I will highlight progress from my laboratory in engineering probiotic microbial cells that have been endowed with functionalities derived from bacteriophages and synthetic nanobodies allowing them to inhibit microbial toxins, kill microbial pathogens and deliver therapeutic molecules. The potential benefits of engineered probiotics are highlighted along with the challenges that must still be met before these intriguing new therapeutic tools can be widely deployed.