Jozef Nissimov
Biography
Research in the Nissimov Lab (the Environmental Virology and Ecology Research Group) focuses on studying the biotic and abiotic factors that affect the dynamic interactions between ecologically important algal and cyanobacterial hosts and their viruses, and their co-evolutionary relationships, in order to elucidate the impact of these dynamics and relationships on natural habitats such as lakes and the ocean. This is achieved through laboratory experimentation and field studies, in which the Nissimov Lab employs cutting-edge molecular biology and microbiology technologies, which include next-generation sequencing, flow cam imaging, analytical flow cytometry, and state-of-the-art photobioreactors and growth chambers for experimental modeling.
The Nissimov Lab also investigates the largely unexplored antiviral potential of bioactive compounds from cyanobacteria and collaborates on the development of novel sequencing approaches and computational tools for studying SARS-CoV-2 and agricultural viruses in wastewater.
Research Interests
Virus Ecology
Environmental Microbiology
Limnology
Marine Biology
Biological Oceanography
Microalgae
Cyanobacteria
Algal Blooms
Aquatic Viruses
Microbial Host-Virus Interactions
Comparative Genomics of Aquatic Viruses
Virus Community Sequencing and Analysis
Bioinformatics
Antimicrobial Discovery
Education
2018 Postdoctoral Fellow, Rutgers University, United States
2013 Ph.D. Biosciences, Plymouth Marine Laboratory & University of Nottingham, United Kingdom
2009 M.Res. Marine Biology, University of Plymouth, United Kingdom
2008 B.Sc. Marine Biology (honours), University of Plymouth, United Kingdom
Awards
2022 Exceptional Service as an ECR Director, Canadian Society for Virology
2021 Norma J. Lang Early Career Research Fellowship, Phycological Society of America
Service
Editorial Board Member, Viruses
Reviewer for PNAS, PlosOne, The ISME Journal, Environmental Microbiology, FEMS Microbiology, Research in Microbiology, Journal of Plankton Research, Virologica Sinica, Virus Genes, Genes, Deep Sea Research Part I, Frontiers in Marine Science, and Scientific Reports
International Committee on Taxonomy of Viruses (ICTV)- Phycodnaviridae Working Group Member
UW’s Trust in Research Undertaking in Science and Technology Scholarly Network (TRuST), Working Group Member
UW’s Faculty Committee on Student Appeals (FCSA), Faculty Committee Member
UW’s Faculty of Science Foundation, Faculty Director (Biology)
Professional Associations
Phycological Society of America
The International Society for Viruses of Microorganisms (ISVM)
Canadian Society for Virology
Phage Canada
Affiliations and Volunteer Work
Interdisciplinary Centre on Climate Change (IC3)
Waterloo Centre for Microbial Research (WCMR)
Water Institute
Teaching*
- BIOL 241 - Introduction to Applied Microbiology
- Taught in 2021, 2022, 2024
- BIOL 442 - Virology
- Taught in 2022, 2024, 2025
- BIOL 450 - Marine Biology
- Taught in 2025
* Only courses taught in the past 5 years are displayed.
Selected/Recent Publications
Meza-Padilla, I., McConkey, B.J. and Nissimov, J.I., 2024. Structural models predict a significantly higher binding affinity between the NblA protein of cyanophage Ma-LMM01 and the phycocyanin of Microcystis aeruginosa NIES-298 compared to the host homolog. bioRxiv, pp.2024-07.
Zheng, S., Lee, V., Meza‐Padilla, I. and Nissimov, J.I., 2024. Antiviral discovery in toxic cyanobacteria: Low hanging fruit in the age of pandemics. Journal of Phycology, 60(2), pp.574-580.
Nash, D., Ellmen, I., Knapp, J.J., Menon, R., Overton, A.K., Cheng, J., Lynch, M.D., Nissimov, J.I. and Charles, T.C., 2024. A novel tiled amplicon sequencing assay targeting the tomato brown rugose fruit virus (ToBRFV) genome reveals widespread distribution in municipal wastewater treatment systems in the province of Ontario, Canada. Viruses, 16(3), p.460.
Lobb, B., Shapter, A., Doxey, A.C. and Nissimov, J.I., 2023. Functional Profiling and Evolutionary Analysis of a Marine Microalgal Virus Pangenome. Viruses, 15(5), p.1116.
Nissimov, J.I., Campbell, C.N., Probert, I. and Wilson, W.H., 2022. Aquatic virus culture collection: an absent (but necessary) safety net for environmental microbiologists. Applied Phycology, 3(1), pp.211-225.
Please see Dr. Nissimov’s Google Scholar profile for a complete list of his published articles: https://scholar.google.bg/citations?user=gdwUR1YAAAAJ&hl=en