D. Spafford
519-888-4567 x38185
Location: 
B1 173

Research Interests:

  • Calcium channel analysis for target drug delivery for treatment of pain, arrhythmias, angina, and potential benefits in treatment of epilepsy and cancer.

  • Structure, function and pharmacology of calcium channels and sodium channels

  • Structure and function and analysis of NALCN cation channel  and anti-calcium channel toxins

  • The Spafford Neurobiology Research Laboratory studies voltage-gated calcium channels, molecular physiology, biophysics, cell biology, protein biochemistry, fluorescence microscopy and tissue cultures.

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[Science News] April 25, 2014 "Waterloo discovers a key regulator in the pacemakers of our brain and heart"

Group(s): 
Application Areas→Biomechanics, Cardiovascular, Neurodegenerative Diseases, Stroke, Targeted Drug Delivery; Technology Areas→Biomarkers, Computational Modeling, Disease Modelling, Drug Development, Imaging; Discipline Areas→Biochemistry, Biology, Biomedicine, Biophysics, Biotechnology, Cell Biology, Pharmacology, Physiology; Faculty→Science

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