Centre for Bioengineering and Biotechnology
University of Waterloo, East Campus 4, Room 2001
200 University Avenue West
Waterloo , Ontario, N2L 3G1 Canada
519-888-4567 Ext 32732
CBB Member Marianna Foldvari, Pharmacy, is focusing on non-invasive gene therapy and drug delivery, using nanotechnology to treat and cure neurodegenerative diseases such as glaucoma.
“A focus right now is to develop nano-sized transporters that can reach the back of the eye to improve vision, especially in the treatment of glaucoma,” Foldvari says.
“Gene therapy is becoming a way where we might even be able to cure diseases, not just treat them,” she says. “Developing gene delivery carriers requires a lot of technological types of development, and this is where nanotechnology comes in. We are now able to develop very small particles outfitted with homing molecules that can deliver the cargo to specific sites. These very small particles can navigate between cells and get to places where older technologies couldn’t. We can also avoid side effects this way because we are very focused on the disease site.”
There is no current cure for glaucoma - the impact of Foldvari's research on healthy aging could be significant.
The University of Waterloo acknowledges that much of our work takes place on the traditional territory of the Neutral, Anishinaabeg and Haudenosaunee peoples. Our main campus is situated on the Haldimand Tract, the land granted to the Six Nations that includes six miles on each side of the Grand River. Our active work toward reconciliation takes place across our campuses through research, learning, teaching, and community building, and is centralized within our Office of Indigenous Relations.