He is particularly interested in the mechanisms, both acute and chronic, whereby energy homeostasis is protected in skeletal muscle. Special attention is being paid to the excitation-contraction coupling processes both with regards to acute and chronic regulation. A number of models are being employed that manipulate both energy availability and energy expenditure. Models designed to reduce energy supply are based on decreasing the availability of oxygen to the muscle cell and include hypoxia, ischemia, hypovolemia and hypervolemia and altitude.
Different exercise protocols are employed to alter energy utilization. Green is also involved in investigating the adaptations that occur in skeletal muscle due to certain diseases and injuries such as chronic heart disease, chronic obstructive lung disease and repetitive strain injury. The effect of these different models on the metabolic organization and the excitation and contraction processes in the muscle cell and the role of changes in these properties on muscle performance, pain and fatigue remain as a central focus.