Centre for Bioengineering and Biotechnology
University of Waterloo, East Campus 4, Room 2001
200 University Avenue West
Waterloo , Ontario, N2L 3G1 Canada
519-888-4567 Ext 32732
There are over half a million Canadians living with dementia. Treatment of this devastating disorder is challenging as there are no drugs available to cure it. Developing a new drug, running clinical trials, and acquiring approval from regulatory agencies is expensive and time-consuming: the process can take decades and cost upwards of 4 billion dollars.
To avoid these barriers, Praveen Nekkar, a professor at the School of Pharmacy at Waterloo, is exploring drug repurposing – the practice of determining new therapeutic uses for drugs that are already approved by regulatory agencies. Nekkar and his group examined a class of drugs called selective serotonin uptake inhibitors (SSRIs). These drugs are typically used in conditions like depression. Nekkar’s team found that they can also play a role in preventing the progression of Alzheimer’s.