John Honek

John Honek

Chemistry, Professor

Biography

John Honek's group works at the interface of chemistry and biochemistry. They apply chemical and biochemical principles and techniques to the problems of protein structure/function as well as to elucidate the chemical mechanisms of several key enzymes, some of which have medical importance.

Organic chemistry (organic synthesis of novel biophysical probes and enzyme inhibitors and protein chemical modification techniques), physical chemistry and molecular modeling are being applied to complex protein structures. His group makes use of biochemical techniques such as recombinant DNA methodologies (PCR, site-directed mutagenesis, protein engineering, etc), microbiology (for protein expression) and protein purification.

Research

Research Interests

  • Bionanomaterials
  • Medicinal chemistry
  • Enzymology
  • Bioorganic chemistry
  • Protein structure and function
  • Drug Discovery, Design and Delivery
  • Biomaterials, Polymers and Bioplastics
  • Biochemistry and Biophysics
  • Bionanotechnology and Biosensors
  • Soft Matter
  • Smart and Functional Materials
  • Molecular Therapeutics and Theranostics
  • Nanomaterials
  • Microbiology

Application Areas

  • Cancer
  • Environmental Biotechnology
  • Industrial Biotechnology
  • Infectious Diseases
  • Targeted Drug Delivery
  • Toxicology
  • Medicinal Chemistry
  • Drug Design
  • Enzymology
  • Protein Engineering

Technology Areas

  • 3D Printing/Additive Manufacturing
  • Biomarkers
  • Biomaterials
  • Computational Modelling
  • Drug Development
  • Imaging
  • Polymer
  • Therapeutics

Discipline Areas

  • Biochemistry
  • Bioinformatics
  • Bionanotechnology
  • Biophysics
  • Bioprocessing/Biochemical Engineering
  • Biotechnology
  • Cell Biology
  • Chemistry
  • Genetic Engineering
  • Nanotechnology
  • Pharmacology
  • Polymer Chemistry
  • Toxicology