Andrea Edginton

Andrea Edginton

School of Pharmacy, Professor, Hallman Director, Associate Dean (Faculty of Science)

Biography

Prof. Edginton’s academic research focuses on the development and application of physiologically-based pharmacokinetic (PBPK) models and simulation techniques in both the areas of pharmaceuticals and human health risk assessment. Her research examines how the physiology of sub-populations such as children and patients with disease affect the pharmacokinetics of drugs and how this information can be integrated into PBPK models for the optimization of drug therapy. Prof. Edginton also heads the modeling component of the Web-Accessible Population Pharmacokinetics Service – Hemophilia (WAPPS-Hemo.org) project that uses population pharmacokinetic modeling and Bayesian forecasting for tailoring treatment prophylaxis in persons with hemophilia.

Research

Research Interests

  • Development and application of physiologically-based pharmacokinetic (PBPK) models and simulation techniques for the guidance of pharmaceutical dosing
  • Population pharmacokinetic modeling and Bayesian forecasting for tailoring treatment prophylaxis in persons with hemophilia
  • Clinical Pharmacology

Application Areas

  • Bleeding Disorders
  • Pharmacokinetic Modeling
  • Pediatrics

Technology Areas

  • Therapeutics

Discipline Areas

  • Pharmacology