- Textbook: Introduction to Proteins: Structure, Function, and Motion by Kessel, A. and Ben-Tal. N, Second Edition, Chapman & Hall/CRC, 2018.
Proteins, with their amazing complexity and diversity, have become increasingly well characterized and even designable, with applications in many areas such as medicine, agriculture, and biotechnology. This course will familiarize students with modern knowledge of proteins. The course will provide an overview of structures of proteins, and their associated functions and dynamics. It will cover an introduction to methods for structure determination and prediction (x-ray crystallography, NMR, cryo electron microscopy, computational methods). Additional topics will include: protein folding and design; protein misfolding and aggregation in disease; recombinant protein production and stable formulation for medical and biotechnological applications. Students will obtain broad experience in: using online resources for finding and using information on protein structure, function and design; group work and peer feedback; reading, synthesizing and assessing, as well as (oral and written) communication of papers from current scientific literature.
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