From Pearson International Airport, Toronto (YYZ):
Take Highway 427 South, exit at Highway 401 West towards London
Keep right on Highway 8 West
Take the exit to merge onto Highway 7 East toward Waterloo, Guelph
Continue on Highway 85 North toward Waterloo
Take the University Avenue West exit
University of Waterloo is on your right
For Google Maps directions
From Region of Waterloo, International Airport (YKF):
Turn right onto Airport Rd
Turn right onto Fountain St N
Turn left onto Woolwich St S
Turn left onto Bridge St E
At the roundabout, take the third exist onto Lancaster St W
Turn right onto Bridgeport Rd E
Turn right onto Albert St
Turn left onto Seagram Dr
University of Waterloo is on your left
For Google Maps directions