Contact Information:
Christian Boudreau
Research interests
Professor Boudreau's research interests include survival analysis, event history analysis, survey sampling, and longitudinal data.
In particular, much of his work has been on analytical inference from longitudinal data collected through complex survey designs involving stratification and clustering. He also has strong research interests in biostatistical methods applied to bone marrow transplant data.
Education/biography
Before joining the University of Waterloo in June 2005, Professor Boudreau was a member of the Division of Biostatistics and of the Center for International Blood and Marrow Transplant Research (CIBMTR) at the Medical College of Wisconsin. He is still involved in collaborative projects on bone marrow research with people at the CIBMTR.
Professor Boudreau is the associate director of the Data Management Core (DMC). The DMC aims to ensure data quality and statistical support for the International Tobacco Control Policy Evaluation Survey. This survey is a longitudinal study of an international cohort of more than 10,000 smokers. The project is in collaboration with Professor Mary E. Thompson (Department of Statistics and Actuarial Science), Doctors Geoffrey T. Fong and David Hammond (Department of Psychology), Doctors K. Michael Cummings, Andrew Hyland, and Richard O'Connor (Roswell Park Cancer Institute, Buffalo, N.Y.), and other international researchers.
When it comes to research the focus of Professor Boudreau's work on longitudinal studies has been on developing methods for estimating spell durations and the effects of various covariates on these durations, when data are collected through large-scale longitudinal surveys. These methods are extensions of the Cox model and of the Breslow-Aalen estimator that adjust for correlation between observations belonging to the same cluster. Examples of applications include the duration of jobless spells in Statistics Canada's Survey of Labour and Income Dynamics, and the duration of spells without health care insurance and on different social programs in the U.S. Survey of Income and Program Participation.
Professor Boudreau has been the leading statistician on various medical research projects on the time to relapse and the time to death following a blood or bone marrow transplant. Such medical procedures rebuild the patient's white blood cells after their destruction by intensive chemotherapy and/or radiation treatment used to kill cancerous cells. The goal of this research is to understand and to estimate, usually by fitting Cox models, the effects of various prognostic factors on these times to events after transplantation.
Selected publications
- Nagelhout, G.E., de Vries, H., Boudreau, C., Allwright, S. et al. (2012), “Comparative impact of smoke-free legislation on smoking cessation in three European countries”, European Journal of Public Health 22 (Suppl 1), 4-9.
- Katsahian, S. & Boudreau, C. (2011), “Testing for centre effects in competing risks: a Monte-Carlo comparison of likelihood ratio and Wald tests”, Statistics in Medicine 30, 1608-1617.
- Reid, J.L., Hammond, D., Boudreau, C. et al. (2010), “Socioeconomic disparities in quit intentions, quit attempts, and smoking abstinence among smokers in four western countries: Findings from the International Tobacco Control (ITC) Four Country Survey”, Nicotine & Tobacco Research 12 (Suppl 1), 20-33.
- Hyland, A., Hassan, L.M., Higbee, C., Boudreau, C., Fong, G.T., Borland, R., Cummings, K.M., Yan, M., Thompson, M.E. & Hastings, G. (2009), "The impact of smokefree legislation in Scotland: Results from the Scottish ITC Scotland/UK longitudinal surveys'', European Journal of Public Health 19, 198–205.
- Lazarus, H.M., Carreras, J., Boudreau, C., et al. (2008), "Influence of age and histology on outcome in adult non-Hodgkin's lymphoma patients undergoing autologous HCT: a report from the Center for International Blood & Marrow Transplant Research (CIBMTR)'', Biology of Blood & Marrow Transplantation 14, 1323--1333.
- Gardner, S.L., Carreras, J., Boudreau, C. et al. (2008), "Myeloablative therapy with autologous stem cell rescue for patients with Ewing sarcoma'', Bone Marrow Transplantation 14, 867-872.
- O'Connor, R.J., McNeill, A., Borland, R., Hammond, D., King, B., Boudreau, C. & Cummings, K.M. (2007), "Smokers' beliefs about relative safety of other tobacco products: finding from the ITC collaboration'', Nicotine & Tobacco Research 9, 1033-1042.
- Vesole, D.H., Pérez, W.S., Akasheh, M., Boudreau, C., Recce, D.E. & Bredeson, C.N. (2006), "High dose therapy and autologous hematopoietic stem cell transplantation for patients with primary systemic amyloidosis : a Center for International Blood and Marrow Transplant Research study", Mayo Clinic Proceedings 81, 880-888.
- Farag, S.S., Bacigalupo, A., Eapen, M., Hurley, C.K., Dupont, B., Caligiuri, M.A., Boudreau, C. et al. (2006) "The effect of KIR ligand incompatibility on the outcome of unrelated donor transplants: a report from the Center for International Blood and Marrow Transplant Research, the European Blood and Marrow Transplant Registry and the Dutch Registry'', Biology of Blood and Marrow Transplantation 12, 876-884.
- Boudreau, C. & Lawless, J.F. (2006), "Survival analysis based on the proportional hazards model and survey data", Canadian Journal of Statistics 34, 203-216.