Please Note: This seminar will be given online.
Distinguished Lecture Series
Stephen
Senn |
Whatever Happened to Design-Based Inference?
What exactly should we think about appropriate analyses for designed experiments and why? If conditional inference trumps marginal inference, why should we care about randomisation? Isn’t everything just modelling? The Rothamsted School held that design matters. Taking an example of applying John Nelder’s general balance approach to a notorious problem, Lord’s paradox, I shall show that there may be some lessons for two fashionable topics: causal analysis and big data. I shall conclude that if we want not only to make good estimates but estimate how good our estimates are, design does matter.
Stephen Senn
Stephen
Senn
has
worked
as
a
statistician
but
also
as
an
academic
in
various
positions
in
Switzerland,
Scotland,
England
and
Luxembourg.
From
2011
to
2018
he
was
head
of
the
Competence
Center
for
Methodology
and
Statistics
at
the
Luxembourg
Institute
of
Health.
He
is
the
author
of
Cross-over
Trials
in
Clinical
Research
(1993,
2002),
Statistical
Issues
in
Drug
Development
(1997,
2007,2021),
Dicing
with
Death
(2003,2022)
and
in
2009
was
awarded
the
Bradford
Hill
Medal
of
the
Royal
Statistical
Society.
In
2017
he
gave
the
Fisher
Memorial
Lecture.
He
is
an
honorary
life
member
of
PSI
and
ISCB.
David A. Sprott (1930-2013)
Professor David Sprott was the first Chair (1967-1975) of the Department of Statistics and Actuarial Science at the University of Waterloo and first Dean of the Faculty of Mathematics (1967-1972). The David Sprott Distinguished Lecture Series was created in recognition of his tremendous leadership at a formative time of our department, as well as his highly influential research in statistical science.