Nima Maftoon

Hearing Lab

The long-term research goal of the Hearing Lab is to develop advanced devices and methods for diagnosis and treatment of hearing loss and other auditory pathologies. Such work requires discoveries about the processes involved in hearing as well as developing innovative engineering solutions. To serve these requirements, we use and advance knowledge in fields such as biomechanics, solid and fluid mechanics, acoustics, system identification and hearing physiology. The research portfolio of the Hearing Lab includes device development, advanced acoustic and vibration measurements and analysis in animal and human ears supplemented with analytical and computational modelling.

Computational Metastasis Lab

Computational Metastasis Lab is focused on developing predictive tools that enable personalized cancer treatments. The lab uses advanced computational mechanics algorithms in conjunction with clinical image processing in creation of the predictive tools. We measure data in vitro and in vivo in human and animals to validate our mathematical models of tumor-cell circulation, intravasation and extravasation using advanced optical methods and using clinical modalities.

• Hearing Science
• Auditory Mechanics
• Medical Devices
• Hearing implants
• Diganostic tools
• Biomechanics
• Vibration
• Acoustics
• Otolaryngology
• Computational Fluid and Solid Mechanics
• Physiological measurements and modelling
• Cancer mechanics
• Metastasis
• Computational Oncology

• 2017, Postdoctoral Fellowship, Postdoctoral Fellowship, Hearing Science and Technology, Otolaryngology, Harvard Medical School, Massachusetts Eye and Ear Infirmary
• 2014, Doctorate, Biomedical Engineering, McGill University
• 2000, Master of Applied Science, Mechanical Enginnering, Isfahan University of Technology
• 1997, Bachelor of Applied Science, Mechanical Enginnering, University of Tehran

• BME 202 - Seminar
  • Taught in 2021
• BME 252 - Linear Signals and Systems
  • Taught in 2018, 2019, 2020, 2021
• SYDE 252 - Linear Systems & Signals
  • Taught in 2019, 2020
• SYDE 750 - Topics in Systems Modelling
  • Taught in 2021

• Mohammadi, Hossein and Ebrahimian, Arash and Maftoon, Nima, Fracture behaviour of human skin in deep needle insertion can be captured using validated cohesive zone finite-element method, Computers in Biology and Medicine, 139, 2021
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• Ebrahimian, Arash and Tang, Haimi and Furlong, Cosme and Cheng, Jeffrey Tao and Maftoon, Nima, Material characterization of thin planar structures using full-field harmonic vibration response measured with stroboscopic holography, International Journal of Mechanical Sciences, 198, 2021
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• Anvari, Sina and Nambiar, Shruti and Pang, Jun and Maftoon, Nima, Computational Models and Simulations of Cancer Metastasis, Archives of Computational Methods in Engineering, 2021
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• Keshavarz, Pouyan and Maftoon, Nima, A systematic approach for developing mechanistic models for realistic simulation of cancer cell motion and deformation, Scientific Reports, 2021
• Shen, J. and Faruqi, A. H. and Jiang, Y. and Maftoon, N., Mathematical Reconstruction of Patient-Specific Vascular Networks Based on Clinical Images and Global Optimization, IEEE Access, 9, 2021, 20648 - 20661
• Anvari, Sina, Osei, Ernest and Maftoon, Nima, Interactions of platelets with circulating tumor cells contribute to cancer metastasis, Scientific Reports, 11(1), 2021
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• Ebrahimian, A. and Mohammadi, H. and Babaie, M. and Maftoon, N. and Tizhoosh, H. R., Class-Aware Image Search for Interpretable Cancer Identification, IEEE Access, 8, 2020, 197352 - 197362
• Tang, Haimi and Razavi, Payam and Pooladvand, Koohyar and Psota, Pavel and Maftoon, Nima and Rosowski, John J. and Furlong, Cosme and Cheng, Jeffrey T., High-Speed Holographic Shape and Full-Field Displacement Measurements of the Tympanic Membrane in Normal and Experimentally Simulated Pathological Ears, Applied Sciences, 9(14), 2019
• Cheng, J. T., Maftoon, N., Guignard, J., Ravicz, M. E., & Rosowski, J., Tympanic membrane surface motions in forward and reverse middle ear transmissions, The Journal of the Acoustical Society of America, 145(1), 2019, 272 - 291
• Motallebzadeh, Hamid and Maftoon, Nima and Pitaro, Jacob and Funnell, W. Robert J. and Daniel, Sam J., Fluid-Structure Finite-Element Modelling and Clinical Measurement of the Wideband Acoustic Input Admittance of the Newborn Ear Canal and Middle Ear, Journal of the Association for Research in Otolaryngology, 18(5), 2017, 671 - 686
• Motallebzadeh, Hamid and Maftoon, Nima and Pitaro, Jacob and Funnell, W. Robert J. and Daniel, Sam J., Finite-Element Modelling of the Acoustic Input Admittance of the Newborn Ear Canal and Middle Ear, Journal of the Association for Research in Otolaryngology, 18(1), 2016, 25 - 48
• Maftoon, Nima and Funnell, W. Robert J. and Daniel, Sam J. and Decraemer, Willem F., Finite-Element Modelling of the Response of the Gerbil Middle Ear to Sound, Journal of the Association for Research in Otolaryngology, 16(5), 2015, 547 - 567
• Keshavarz-Motamed, Zahra and Garcia, Julio and Gaillard, Emmanuel and Maftoon, Nima and Labbio, Giuseppe Di and Cloutier, Guy and Kadem, Lyes, Effect of coarctation of the aorta and bicuspid aortic valve on flow dynamics and turbulence in the aorta using particle image velocimetry, Experiments in Fluids, 55(3), 2014, 1 - 16
• Maftoon, Nima and Funnell, W. Robert J. and Daniel, Sam J. and Decraemer, Willem F., Effect of Opening Middle-Ear Cavity on Vibrations of Gerbil Tympanic Membrane, Journal of the Association for Research in Otolaryngology, 15(3), 2014, 319 - 334
• Maftoon, Nima and Funnell, W. Robert J. and Daniel, Sam J. and Decraemer, Willem F., Experimental Study of Vibrations of Gerbil Tympanic Membrane with Closed Middle Ear Cavity, Journal of the Association for Research in Otolaryngology, 14(4), 2013, 467 - 481
• Funnell, W. Robert J. and Maftoon, Nima and Decraemer, Wilem F., Modeling of Middle-Ear Mechanics, The Middle Ear - Science, Otosurgery, and Technology, Puria, Sunil and Fay, Richard R. and Popper, Arthur N., , 39 manuscript pages