Marc Aucoin

Marc Aucoin

Chemical Engineering, Professor, Associate Chair, Operations

Biography

Marc Aucoin is the Associate Chair, Operations and a Professor in the Department of Chemical Engineering. He specializes in Biochemical Engineering, particularly in cell culture engineering for the production of complex biologics: from proteins (projects have included work on myristoylated proteins, antibodies and other immune-system related proteins), to DNA, to virus-like particles, viruses and viral vectors.

Professor Aucoin’s research work makes use of several cell culture platforms including insect (Sf9, Hi5) and mammalian cells (CHO, Vero). One aspect of Prof. Aucoin's work involves the use of 1D-1H NMR for optimizing cell culture processes.

Through his work with viruses, Prof. Aucoin has also gained an interest in examining the stability of virus in complex solutions including cell culture media. This has led to collaborations with industry in the area of virus inactivation and virus control.

At the University, Prof. Aucoin is also a Faculty Advisor for the university’s international Genetically Engineered Machine (iGEM) competition student team. Prof. Aucoin is an active member of the Centre for Bioengineering and Biotechnology and the Waterloo Centre for Microbial Research. He is also a member of the Waterloo Institute for Nanotechnology. More information can be found on his personal website.

Research

Research Interests

  • Virus propagation
  • Viral vector
  • Virus-like particle
  • Vaccine production
  • Infection
  • Gene delivery
  • Animal cell culture
  • Biochemical & Biomedical
  • Mammalian cell
  • Metabolism
  • Bioprocess development
  • Monoclonal Antibody Production and Modification
  • Biologic Production
  • Baculovirus Expression Vectors
  • Serological Assays
  • Cell Culture Monitoring
  • Modeling and Simulation
  • Synthetic Biology

Application Areas

  • Cancer
  • Industrial Biotechnology
  • Infectious Diseases
  • Inflammatory Diseases
  • Pathogen Detection

Technology Areas

  • Biomarkers
  • Gene Therapy
  • Microbiome
  • Therapeutics
  • Vaccines

Discipline Areas

  • Biochemistry
  • Biology
  • Biomedical Engineering
  • Bionanotechnology
  • Bioprocessing/Biochemical Engineering
  • Biosystem Engineering
  • Biotechnology
  • Cell Biology
  • Genetic Engineering
  • Genome Engineering
  • Industrial Biotechnology
  • Synthetic Biology