Nicole Noel

Dr. Nicole Noel is a photoreceptor biologist and ocular geneticist interested in how photoreceptors, the light-detecting cells in the retina, are built to enable vision and are impacted by ageing and disease.

• Photoreceptor biology (function, development, connectivity, ageing/disease)

• Comparative neuroscience

• Ocular genetics

• Disease modelling

• Nicole C. L. Noel*. Ordered chaos: Photoreceptor mosaics in the larval and adult turquoise killifish (Nothobranchius furzeri). (2026) Journal of Comparative Neurology, 534(9): e70199. doi: 10.1002/cne.70199

• Steven Bergmans, Nicole C. L. Noel, Luca Masin, Ellen G. Harding, Aleksandra M. Krzywańska, Julię D. De Schutter, Rajagopal Ayana, Chi-Kuo Hu, Lut Arckens, Philip A. Ruzycki, Ryan B. MacDonald*, Brian S. Clark*, and Lieve Moons*. (2024) Age-related dysregulation of the retinal transcriptome in African turquoise killifish. Aging Cell, 23(8): e14192. doi: 10.1111/acel.14192

• Aanandita Kothurkar, Gregory Patient, Nicole C. L. Noel, Aleksandra M. Krzywańska, Colin Chu*, and Ryan B. MacDonald*. (2024) ‘Iterative Bleaching Extends Multiplexity’ facilitates simultaneous identification of all major retinal cell types. Journal of Cell Science,137(23): jcs263407. doi: 10.1242/jcs.263407

• Nicole C. L. Noel*, W. Ted Allison, Ian M. MacDonald, and Jennifer C. Hocking. (2022) Zebrafish and inherited photoreceptor disease: Models and insights. Progress in Retinal and Eye Research, 91: 101096. doi: 10.1016/j.preteyeres.2022.10109

• Lance P. Doucette, Nicole C. L. Noel, Manlong Xu, Yi Zhai, Oana Caluseriu, Stephanie C. Hoang, Alina J. Radziwon, and Ian M. MacDonald*. (2021) Whole exome sequencing reveals putatively novel associations in retinopathies and drusen formation. European Journal of Human Genetics, 29(8): 1171–1185. doi: 10.1038/s41431-021-00872-3

• Nicole C. L. Noel*, Nathan J. Nadolski, Jennifer C. Hocking, Ian M. MacDonald, and W. Ted Allison. (2020) Progressive photoreceptor dysfunction and age-related macular degeneration-like features in rp1l1 mutant zebrafish. Cells, 9(10): 2214. doi: 10.3390/cells9102214

• For a complete list of Dr. Noel's publications, please see [https://scholar.google.com/citations?user=-NzamnkAAAAJ&hl=en&oi=ao).