A new University of Waterloo study shows that current Hepatitis B vaccination, screening, and treatment strategies in Ontario will leave the province well short of its goal to reduce preventable infections that afflict 1,000 Ontarians annually.
The report's authors developed a computer model simulating the long-term effects of existing Hepatitis B virus (HBV) prevention and treatment strategies in Ontario. "We found that even if current strategies were increased, Ontario would continue to struggle to eliminate new HBV cases and decrease liver-related deaths and HBV-induced cancers," said William W.L. Wong, a professor at Waterloo's School of Pharmacy and the study's lead researcher.
While there is a vaccine to prevent HBV and antiviral treatments to suppress the virus if the patient develops chronic (long-lasting) hepatitis B, vaccination, screening, and treatment strategies are often logistically challenging and expensive.
Several high-income countries, including Canada, have committed to achieving World Health Organization (WHO) goals to decrease new cases of HBV by 95 per cent and to decrease HBV-related deaths by 65 per cent by 2030.
"We found that existing HBV prevention and treatment strategies in Ontario would only decrease cases of acute hepatitis by 64.5 per cent, decrease HBV-related decompensated cirrhosis by 9.4 per cent and decreases liver cancer by 10.5 per cent between 2015 and 2030," Wong said. "However, the incidence of chronic HBV would increase by 26.6 per cent, and liver-related deaths would increase by one per cent in the same time frame."
Read the full story on the Waterloo News website.