Join us for a CERC Research Lecture by Professor Ruibing Wang PHD, FRSC.
Abstract:
Cells, as the fundamental units of life, represent powerful and naturally optimized drugs or drug delivery vehicles. To harness this potential, we have established a "supramolecular cell engineering" approach to targeted therapy. This technique uses non-covalent chemistry to self-assemble nanomedicines and biomaterials directly onto or inside cells. By functionally engineering the surface or interior of cells—such as leveraging the inflammatory tropism of immune cells—we create emerging targeted cell therapeutics. We have demonstrated that these engineered cells can deliver therapeutics with high efficiency to diseased tissues, treating inflammatory diseases, cardiovascular disease, and solid tumors. This supramolecular cell engineering strategy opens a new frontier in cell-based therapeutics, and we are just beginning to explore its vast potential.
About the Speaker:
Prof. Ruibing Wang is a Full Professor of Supramolecular Biomaterials at the University of Macau. He earned his BSc from Jilin University and his PhD from Queen’s University. His research focuses on supramolecular biomaterials, cell-mimetics, and cell-based therapeutics. With over 270 publications in prestigious journals such as Matter, Nat. Commun., Sci. Adv., JACS, Angew. Chem. Int. Ed, and Adv. Mater. his work has garnered over 14,350 citations and an H-index of 68 (Google Scholar). As a recipient of multiple Macau Science and Technology Awards and Teaching Excellence Award, he is consistently ranked among Stanford's World's Top 2% Scientists. Prof. Wang also serves as an international grant examiner for multiple national funding agencies, and an Associate Editor for ACS Applied Bio Materials and Chinese Chemical Letters.