MASc Oral Exam | Sequentially entrapped enzymes in 3D-printed PMMA microfluidic reactors for the synthesis of amorphadiene via the IUP, by Derk Kabernick

You are welcome to attend Derek Kabernick MASc oral exam supervised by Professor V. Ward

Abstract:

Expanding upon the current fields of cascade immobilized enzyme systems and isoprenoid synthesis, in this study, additive manufacturing was used to entrap enzymes during 3D-printing for the fabrication of sequentially immobilized microfluidic reactors to synthesize amorphadiene, a precursor to the antimalaria drug artemisinin, in vitro via the IUP. Kinetic characterization of the pathway enzymes were performed for modelling and optimization of pathway flux in COMSOL Multiphysics..