Seminar - “Biomaterials Topography for Stem Cell Regulation and Tissue Engineering Applications”, Evelyn KF Yim, Department of Biomedical Engineering, Mechanobiology Institute Singapore, Department of Surgery, National University of Singapore
ABSTRACT: Stem cells respond to both physical and biochemical changes in their stem cell niche. An ideal scaffold for tissue engineering application should mimic the microenvironment for natural tissue development and present the appropriate biochemical and topographical cues in a spatially controlled manner. Studies have shown that physical forces from the substrate topography play a role in stem cell proliferation, migration and cell fate determination.