CHE Seminar | Mario Jolicoeur: Modelling Cell Behaviour for the Identification of Biomarkers
Our approach to mathematically describing a cell population behaviour has evolved in the past decades. From the use of Monod kinetics, when a limiting nutrient shows to control cell behaviour, we now see modelling approaches based on a genome-wide description of a biosystem, integrating the various “omics” datasets available. However, do we always need that level of complexity to face a problem of bioprocess optimization or to elucidate the mechanisms of a metabolic disease?