Thursday, October 17, 2013 3:30 pm
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3:30 pm
EDT (GMT -04:00)
Park and Veva Reilly Distinguished Seminar, "Design, Characterization and Applications of Amphipathic Peptides for sRNA Delivery" by Dr. Mousa Jafari
Mousa Jafari, PhD
Post-Doctoral Fellow
University of Waterloo
RNA interference is a post-transcriptional gene silencing process whereby short interfering RNAs (siRNAs) induce the sequence-specific degradation of complementary messenger RNA. Despite their promising therapeutic capabilities, siRNA-based strategies suffer from enzymatic degradation and poor cellular uptake. Several carrier-based approaches have been employed to enhance the stability and efficiency of siRNA delivery.