Seminar - “Modelling Vascular Cell Response to Hemodynamic Forces: The Importance of Geometry” by Richard L. Leask, Associate Professor, Department of Chemical Engineering, McGill University
ABSTRACT: Vascular cells adapt and respond to biomechanical forces. The focal nature of most cardiovascular diseases has been linked to a dysfunctional response of endothelial cells and blood components to local hemodynamic forces. My lab studies the role of hemodynamic forces in the initiation, progression and treatment of cardiovascular diseases. In this talk I will present work we have done using three dimensional cell culture models to simulate the vascular hemodynamic environment in order to answer questions on how endothelial cells (ECs) and blood components respo