A pill exploding a microbe
Tuesday, February 20, 2024

Researchers are using RNA in a new approach to fight HIV

You know mRNA, now meet siRNA

Society learned about the value of mRNA during the COVID-19 pandemic when we saw scientists and medical professionals harness its power to deliver a vaccine for the virus within a year.

Now, University of Waterloo pharmacy associate professor Emmanuel Ho has developed a novel nanomedicine loaded with genetic material called small interfering RNAs (siRNA) to fight human immunodeficiency virus (HIV) using gene therapy. These siRNAs regulate which genes or proteins are turned on or off in our cells and showed a 73 per cent reduction in HIV replication.

This opens the door for new therapeutics in the fight against HIV.

EMMANUEL HO, Associate Professor, Waterloo Pharmacy

Read more on Waterloo News.