J.M. Gamble

• post-marketing drug safety and effectiveness
• comparative safety and effectiveness
• pharmacoepidemiology
• diabetes health outcomes
• drug information science

Dr. Gamble conducts drug safety and effectiveness research using epidemiologic methods. His team generates new evidence of drug effects through knowledge syntheses and observational drug effect studies in the area of diabetes pharmacotherapy. 

Dr. Gamble’s other research interests include knowledge translation of drug information, evidence-based monitoring of medications, and pharmaceutical policy evaluation.

Dr. Gamble teaches at both the undergraduate and graduate level. His primary teaching responsibilities include:

• PHARM 222: Integrated Patient Focused Care 3

Graduate courses in development.

• Anand K, Sketris I, Zhang Y, Levy A, Gamble JM. The impact of FDA and Health Canada warnings related to the safety of high dose simvastatin. Drugs – Real World Outcomes 2017 (in press).
• Abu-Ashour W, Twells LK, Valcour J, Randell A, Donnan J, Howse P, Gamble JM. The Association Between Diabetes Mellitus and Incident Infections: A Systematic Review and Meta-Analysis Of Observational Studies. BMJ Open Diabetes Res Care 2017;5:e000336. DOI: 10.1136-bmjdrc-2016-000336 PMID: 28761647.
• Gamble JM, Chibrikov E, Twells LK, Midodzi WK, Young SW, MacDonald D, Majumdar SR. Association of insulin dosage with mortality or major adverse cardiovascular events: a retrospective cohort study. Lancet Diabetes Endocrinol 2017;5:43-52. DOI: 10.1016/S2213-8587(16)30316-3 PMID: 27865756.
• Howse PM, Chibrikova LN, Barrett BJ, Twells LK, Gamble JM. Safety and Efficacy of Incretin-based Therapies in Patients with Type 2 Diabetes and Chronic Kidney Disease: Systematic Review and Meta-analysis. Am J Kidney Dis 2016; 68:733-742. DOI: 10.1053/j.ajkd.2016.06.014 PMID: 27528374
• Gamble JM, Thomas JM, Twells LK, Midodzi WK, Majumdar SR. Comparative Effectiveness of Incretins and the Risk of Death and Cardiovascular Events In 38233 New Metformin Users. Medicine 2016;95:26. DOI: 10.1097/MD.0000000000003995 PMID: 27368005.
• Gamble JM, Clarke A, Myers KJ, Agnew MD, Hatch K, Snow MM, Davis EM. Incretin-based medications for type 2 diabetes: an overview of reviews. Diabetes Obes Metab 2015;17:649-658. DOI: 10.1111/dom.12465 PMID: 25772666
• Gamble JM. An Introduction to the Fundamentals of Cohort and Case-Control Studies. Can J Hosp Pharm 2014;67:366-372. Available: http://www.cjhp-online.ca/index.php/cjhp/article/view/1391/2014  PMID: 25364019
• Gamble JM, Hall JJ, Marrie TJ, Sadowski CA, Majumdar SR, Eurich DT. Medication Transitions and Polypharmacy in Older Adults Following Acute Care. Therapeutics and Clinical Risk Management 2014;10:189-196. DOI: 10.2147/TCRM.S58707 PMID: 2467223
• Gamble JM, Majumdar SR, Johnson JA, McAlister FA, Simpson SH, Eurich DT. Changes in Thiazolidinedione Use and Outcomes Following Removal of a Prior Authorization Policy: Controlled Time-Series Analysis. Med Care 2014;52:47-55. DOI: 10.1097/MLR.0000000000000006 PMID: 24309670

• Primary Healthcare Researcher of the Year, Memorial University, 2017
• New Investigator Award, Canadian Institutes of Health Research, 2013-2018
• Clinician Scientist Award, Canadian Diabetes Association, 2013-2018
• Dean George A Burbidge Memorial Award, Canadian Pharmacists Association, 2005

• Member, CIHR College of Reviewers (Sept. 2017 – present)
• Board Member, Canadian Association of Population Therapeutics (Nov 2015 - present)
• Member, Diabetes Canada Clinical & Scientific Section (2009 – present)
• Member, International Society for Pharmacoepidemiology (2008 – present)

2012, PhD Public Health Science (University of Alberta)

2008, MSc Clinical Epidemiology (University of Alberta)

2005, BSc Pharmacy (University of Alberta)

2001, BSc Biology (Lakehead University)