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Tuesday, September 9, 2014 3:00 pm - 3:00 pm EDT (GMT -04:00)

Seminar - “Engineering Anticancer Bacterial Therapies”, by Professor Neil Forbes, Department of Chemical Engineering,University of Massachusetts, Amherst, MA

ABSTRACT:  Engineered bacteria have the potential to overcome the limitations that cause common cancer therapies to fail. Synthetic biology is playing a critical role in the creation of these therapies. We have shown that bacteria, specifically Salmonella, have three main qualities that enable them to overcome the limitations of chemotherapy. Bacteria 1) preferentially target tumors, 2) penetrate tissue, and 3) can kill non-mitotic cells.

Thursday, July 24, 2014 11:30 am - 11:30 am EDT (GMT -04:00)

Seminar - “Design of Pharmaceutical and Protein Crystallizers: Using Multiphase Flow and Controlled Dynamic Operations” by Mo Jiang, PhD, Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA

ABSTRACT: Crystallization is important for pharmaceuticals, amino acids, and proteins. The first part of this seminar will discuss the crystallization of small-molecule organic chemicals such as pharmaceuticals and amino acids. The crystal size distribution (CSD) can affect the efficacy of drug products (such as the amount of drug reaching the lungs from a nasal spray) as well as the efficiency of downstream processes such as filtration and milling.