Pu Chen is a Professor in the Department of Chemical Engineering and a member of the Waterloo Institute of Nanotechnology at the University of Waterloo. He is also the Canada Research Chair in Biomanufacturing.
Professor Chen’s research is at the interface of materials, biomedicine and energy. It involves the application of physical chemistry, surface thermodynamics, solid state physics, biochemistry and molecular cell biology to biomedical and chemical engineering systems.
He aims to design and measure the molecular interaction, nanostructure formation and adsorption kinetics of peptides, DNA, Small Interfering RNA (siRNA), proteins, surfactants and polymers in solution or at interfaces. The research applies techniques emerging from innovations in nanotechnology, genomics, proteomics and nano/microelectronics to issues found in nanomedicine, biomaterials, colloid and surface science.
Practical applications of Professor Chen’s research include drug and gene delivery; peptide-DNA/RNA binding; protein-lipid interactions, lipid bilayer and cell membrane actions; therapeutic lung surfactants; and emulsification, coating, painting, and thin films. His research also applies to surface mass and heat transfer; molecular/microsensors; nanotube membranes and bioseparation; biofuel cells; molecular sensing and nanocellular foaming of polymers. Professor Chen’s lab has significantly impacted the success of many emerging energy, biomedical and chemical technologies. His research has also resulted in the creation of a start-up company that works with nano-peptide technology.
In addition to Professor Chen’s research work, he is the author and co-author of 20 refereed journal publications. He has also written “Molecular Interfacial Phenomena of Polymers and Biopolymers”, as well as 9 book chapters.
- Nanotechnology & Nanomedicine
- Biochemical & Biomedical
- Separation Processes
- Surfaces And Interfaces
- Physical Chemistry
- Drug And Gene Delivery (siRNA And Anticancer)
- Interfacial Phenomena
- Colloids & Porous Media
- Materials Science
- Surface Thermodynamics
- Solid State Physics
- Additive Manufacturing
- 1998, Doctorate, Mechanical Engineering, University of Toronto
- 1993, Master's, Materials Science, University of Toronto
- 1988, Bachelor of Science (BSc), Materials Science, Nanjing University
- 1985, Bachelor's, Physics, Nanjing University
- CHE 231 - Physical Chemistry 2
- CHE 612 - Interfacial Phenomena
- CHE 755 - Res Topics in Electrochemical Engineering, Interfacial Eng & Material Science
- Hasan, M.M., Li, Y.G., Li, G., Park, C.B., Chen, P. and Simha, R., "Determination of Solubilities of CO2 in Linear and Branched Polypropylene Using a Magnetic Suspension Balance and a PVT Apparatus," Journal of Chemical Engineering Data, 55 (11), 4885-4895 (2010). (Accepted in 2010)
- Y. Sheng, W. Wang and P. Chen, "Interaction of an ionic complementary peptide with a hydrophobic graphic surface," Protein Science, (accepted, 2010). (Accepted in 2010)
- M. Yan, D. Yang, Y. Deng, H. Lou, P. Chen and X. Qiu, "Influence of pH on the behavior of lignosulfonate macromolecules in aqueous solution," Colloids and Surfaces A: Physicochem. & Eng. Aspects, 371, 50-58 (2010). (Accepted in 2010)
- Young-Mi Hwang, Peter Stathopulos, Kristin Dimmick, Hong Yang, Hamid Badiei, Mingsze Tong, Jessica Rumfeldt, P. Chen, Vassili Karanassios, and Elizabeth Meiering, "Pathological aggregation from the holo state of Cu/Zn superoxide dismutase in ALS," J. Biol. Chem., (accepted, 2010). (Accepted in 2010)
- P. Sadatmousavi, M. Soltani, R. Nazariann, M. Jafari and P. Chen, "Self-assembling peptides: potential role in tumor targeting," Current Pharmaceutical Biotechnology, (accepted, 2010). (Accepted in 2010)