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A. Russell Tupling

Professor, Associate Chair for Undergraduate Studies
Associate Chair for Undergraduate Studies<--break->

Contact

Office: BMH 3024

Phone: 519-888-4567, ext. 33652

Email: rtupling@uwaterloo.ca

Website: SERCA Pumps in Muscle, Metabolism and Physiology Lab

Russ Tupling

Research interests

We study the sarco(endo)plasmic reticulum Ca2+-ATPase or SERCA pump in the sarcoplasmic reticulum (SR), which, together with other important SR proteins, make up the membrane system that regulates calcium inside the muscle cells of our bodies.  Our research focuses on understanding: 1) the overall regulation of SR function in muscle and how defects in the structure/function of SR proteins cause Ca2+ handling abnormalities that contribute to fatigue, weakness and disease and  2)the factors involved in regulating Ca2+ transport efficiency by SERCA pumps and to determine if alterations in Ca2+ transport efficiency can affect metabolic rate and susceptibility to diet-induced obesity and type II diabetes.

Graduate supervision and student opportunities

  • Research volunteer
  • Undergraduate thesis
  • MSc thesis
  • Coursework interns
  • PhD thesis
  • Post Doctoral Fellowship

Teaching, expertise, tools and technologies

  • Muscle Physiology
  • Obesity, diabetes and metabolism

Courses

KIN 205: Muscle Physiology in Exercise and Work

KIN 404: Physiological Basis of Obesity and Type 2 Diabetes

KIN 601: Muscle Physiology

Education

PhD (Waterloo)

​Selected publications

See Google Scholar for full list of publications.

Affiliation: 
University of Waterloo