A. Russell Tupling

Research interests

We study the sarco(endo)plasmic reticulum Ca^2+-ATPase or SERCA pump in the sarcoplasmic reticulum (SR), which, together with other important SR proteins, make up the membrane system that regulates calcium inside the muscle cells of our bodies.  Our research focuses on understanding: 1) the overall regulation of SR function in muscle and how defects in the structure/function of SR proteins cause Ca²⁺ handling abnormalities that contribute to fatigue, weakness and disease and  2)the factors involved in regulating Ca²⁺ transport efficiency by SERCA pumps and to determine if alterations in Ca²⁺ transport efficiency can affect metabolic rate and susceptibility to diet-induced obesity and type II diabetes.

Graduate supervision and student opportunities

• Research volunteer
• Undergraduate thesis
• MSc thesis
• Coursework interns
• PhD thesis
• Post Doctoral Fellowship

Please email me to discuss current available opportunities.

Graduate studies application details

Teaching, expertise, tools and technologies

• Muscle Physiology
• Obesity, diabetes and metabolism

Courses

KIN 404: Physiological Basis of Obesity and Type 2 Diabetes

KIN 601: Muscle Physiology

Education

PhD, University of Waterloo

​Selected publications

See Google Scholar for full list of publications.