No longer supervising new students
Education
BSc Nursing (1974, University of British Columbia)
MSc Health Care and Epidemiology (1982, University of British Columbia)
PhD Epidemiology (1989, Columbia University)
Teaching interests
Epidemiologic methods, mental health, public health.
Courses
HLTH 442 Chronic disease epidemiology
HLTH 472 Populations aspects of child and adolescent mental health
HSG 606 Epidemiologic methods
Research goals
My primary research focuses on two main areas: study of prognostic factors in psoriatic arthritis (PsA) and study of gene-environment interactions in schizophrenia. Similar to rheumatoid arthritis and lupus erythematosus, individuals with PsA experience increased morbidity, mortality, pain and disability compared with the general population. The identification of factors that influence course of PsA may help to improve treatment and management and ultimately reduce illness burden. Like most complex disorders, the susceptibility to schizophrenia is believed to be due to multiple genes and interacting non-genetic factors. especially during the period from conception to childhood and adolescence. In families demonstrating genetic predisposition to schizophrenia involving the NOS1AP gene, my colleagues and I have investigated the role of childhood trauma and other commonly measured childhood adversities, including physical illness and cannabis use on the expression of schizophrenia in this familial sample, independent of measured genetic risk.
Major funding sources
- National Alliance for Research on Schizophrenia and Depression (NARSAD)
- Canadian Institutes of Health Research (CIHR)
Selected publications
-
Husted J, Ahmed R, Chow EWC, Brzustowicz LM, Bassett AS (in press). Early environmental exposures influence schizophrenia expression even in the presence of strong genetic predisposition. Schizophrenia Research.
-
Lineker S, Husted J, Brown KS (2012). Discipline of provider and model of care influence impact of an athritis educational intervention in primary care. Arthritis Care & Research. doi:10.1002/acr.20694.
-
Husted J, Tom B, Farewell V, Gladman D (2012 January 09) A longitudinal study of the bi-directional association between pain and depressive symptomatology in patients with psoriatic arthritis. Arthritis Care & Research. doi:10.1002/acr.21602.
-
Husted J, Tom B, Farewell V, Gladman D (2010). Longitudinal characteristics of fatigue in psoriatic arthritis. Journal of Rheumatology, 37:1878-1884.
-
Husted J, Ahmed R, Chow EWC, Brzustowicz LM, Bassett AS (2010). Childhood trauma and genetic factors in familial schizophrenia associated with the NOS1AP gene. Schizophrenia Research, 121:187-192.
-
Husted J, Lim S, Chow EWC, Greenwood C, Bassett AS (2009). Heritability of neurocognitive traits in familial schizophrenia. American Journal Medical Genetics B Neuropsychiatric Genetics, 150B:845-853.
-
Husted J, Tom B, Farewell V, Schentag C, Gladman DD (2007). A longitudinal study of the effect of disease activity and clinical damage on physical function over the course of psoriatic arthritis. Does the effect change over time? Arthritis & Rheumatism, 56:840-849.