My lab seeks to better understand how and why vascular disease is accelerated by complex blood flow (e.g., recirculation) and abnormal vascular wall properties. My lab is focused on three main lines of investigation:
- Control of complex blood flow and wall motion in conduit arteries and veins
- Impact of sedentary behaviour and exercise on vessel risk exposure
- Discovery of novel outcomes of vascular disease progression and severity
These areas are supported by an integrative physiology program that combines next-generation ultrasound imaging, human dose-response models, and exercise training interventions for a comprehensive understanding of vascular health.
Graduate supervision and student opportunities
- Research volunteer
- Undergraduate thesis
- MSc thesis
- Coursework interns
- PhD thesis
- Postdoctoral Fellowship
Please email me to discuss current available opportunities.
Teaching, expertise, tools and technologies
- Cardiovascular exercise physiology
- Blood flow
- Arterial stiffness
- Arterial bifurcations
- High frame rate ultrasound
BSc Kinesiology, McMaster University
PhD Kinesiology, McMaster University
PDF Electrical & Computer Engineering, University of Waterloo
See PubMed for full list of publications.
Au JS, Yiu BYS, So H, Chee AJY, Greaves DK, Hughson RL, Yu ACH. Vector projectile imaging for detection of altered carotid bifurcation hemodynamics during reductions in cardiac output. Med Physics, 2019, in press, DOI: 10.1002/mp.13905
Au JS, Yiu BYS, Yu ACH. Visualization of blood recirculation in a femoral artery ‘trifurcation’ using vector flow imaging. J Appl Physiol, 2019, 127:1809-1813.
Au JS, Bochnak PA, Valentino SE, Cheng JL, Stöhr EJ, MacDonald MJ. Cardiac and haemodynamic influence on carotid artery longitudinal wall motion. Exp Physiol, 2018, 103(1):141-152.
Au JS, Valentino SE, McPhee PG, MacDonald MJ. Diastolic carotid artery longitudinal wall motion is sensitive to both aging and coronary artery disease status independent of arterial stiffness in humans. Ultrasound Med Biol, 2017, 43(9):1906-1918.
Au JS, Oikawa SY, Morton RW, MacDonald MJ, Phillips SM. Arterial stiffness is reduced regardless of resistance training load in young men. Med Sci Sports Exerc, 2017, 49(2):342-348.