Department of Biology
ESC 350
200 University Ave. W
Waterloo, Ontario,
Canada N2L 3G1
Phone: (519) 888-4567 ext. 32569
Fax: (519) 746-0614
Professor, University Research Chair
Zoya Leonenko's research focuses on the study of biophysics of lipids and lipid-protein interactions.
Contact information
Office: PHY 354
Phone: 519-888-4567, ext. 38273
Lab: PHY 335
Email: zleonenko@uwaterloo.ca
Website: Nanoscale Biophysics Group
Expertise
- Biophysics of lipids and lipid-protein interactions
- The role of structural changes and physical properties of lipid template in controlling biological processes and diseases
- Application of lipid films in biomedical nanotechnology
- Fluorescence and atomic force microscopy
- Kelvin probe force microscopy
- Single molecule force spectroscopy
Research Program
- Scope: Biophysics of lipids and lipid-protein interactions; role of structural changes and physical properties of lipid monolayers and bilayers in controlling biological processes and diseases; application of lipid films in biomedical nanotechnology
- Current Research Projects: role of lipid membrane in amyloid toxicity in relation to Alzheimer's Disease; testing amyloid inhibitor drugs using single molecule atomic force spectroscopy, interaction of antimicrobial peptides with lipid membrane and lung surfactant; lipid-based drug delivery systems, developing novel biosensing platforms using lipid membrane and surface enhanced spectroscopy
- Methods: Optical, Fluorescence and Scanning Probe Microscopy (SPM) such as Atomic Force Microscopy (AFM), Kelvin Probe Force Microscopy (KPFM) and AFM-based Force Measurements; Langmuir-Blodgett Monolayer Technique; Surface Enhanced Spectroscopy; Novel Biological Applications of Frequency Modulation KPFM (FM-KPFM) Technique
- Research is funded by: Natural Sciences and Engineering Research Council of Canada (NSERC), Canadian Institute for Health Research (CIHR), Canada Foundation for Innovation (CFI), Ontario Ministry of Research & Innovation
- Dr. Zoya Leonenko and her research group are actively looking for commercial partners. Please contact Dr. Zoya Leonenko at zleonenk@uwaterloo.ca
Teaching
Professor Leonenko teaches both undergraduate and graduate courses. Course offerings have included
- BIOL/PHY 280 Introduction to Biophysics
- PHY 437 Physics Honours Projects
- PHY 490 Special Topics
- BIOL 499 Biology Honours Project
- BIOL 681 Reading Course
- NANO 701 Biomedical Nanotechnology
Highlighted Publications
Please see Zoya Leonenko's Google Scholar profile for a current list of her peer-reviewed articles.
Awards and Distinctions
- 1995 Second Prize, Ph.D. student competition in Chemical Physics, Siberian Branch of the Russian Academy of Sciences
- 1992-1996 Ph.D. Scholarship, Russian Academy of Sciences
- 2002 Eli Lilly Conference Travel Award
- 2005 IUPAB Conference Travel Award
- 2005 NATA Advanced Study Institute Participant
- 2006 Invited Professorship Award, University of Burgundy, Dijon, France
- 2008-2012 NSERC University Faculty Award
- 2011 Invited Professorship Award, University of Burgundy, Dijon, France
University of Waterloo Affiliations
- Jointly-appointed with Physics & Astronomy
- Graduate Nanotechnology Program Development, Member of Coordinating Committee
- Waterloo Institute for Nanotechnology
Professional Associations and Service
- Journal Editorship
- Journal of NanoBiomedicne and Engineering (NBE)
- PLOS ONE
Degrees
1996 PhD Institute of Chemical Kinetics and Combustion, Russian Academy of Sciences, Novosibirsk, Russia
1985 BSc & MSc Novosibirsk State University, Russia
Affiliation:
University of Waterloo