Laura Hug
Biography
Dr. Laura Hug is an Associate Professor in the Department of Biology whose research examines the diversity and function of microbial communities in contaminated sites.
Research in the Hug lab seeks to define microbial diversity and function at contaminated sites (primarily municipal landfills). Her lab sequences the total DNA, RNA and protein (meta-omics) of microbial communities to identify which organisms are there, and which pathways are active. She uses enrichment culturing to explore microbial community interactions and to develop new bioremediation tools. The combination of genome-enabled metabolic prediction with tracking contaminant degradation in the lab clarifies how microbes are shaping the environment. Beyond developing tools for environment remediation, the Hug lab examines essential questions in biology – how do organisms adapt to the harsh conditions at contaminated sites? How and when did the ability to degrade a man-made product evolve? In what ways are microbial communities more than the sum of their parts, and do these interactions drive global cycles? Her research expands our understanding of the tree of life, while simultaneously developing solutions to emerging and priority contaminants.
Hug’s research addresses anthropogenic environmental change by studying microorganisms that mitigate methane emissions and degrade human‑made contaminants such as plastics and solvents. Her work aims to directly apply scientific discoveries to ongoing environmental challenges, with a focus on reducing the impacts of human activities on the environment. By exploring both the diversity of life and its resilience, her research supports more sustainable stewardship of Earth’s ecosystems.
Research Interests
Microbial diversity and function
Contaminated site microbial ecology
Total community (meta-omic) analyses, including metagenomics (DNA), metatranscriptomics (RNA), and proteomics (proteins)
Bioremediation
Bioinformatics, systematics and evolution
Protection of surface and groundwater resources
Education
2012, PhD Cell and Systems Biology, University of Toronto, Canada
2007, MSc Biochemistry and Molecular Biology, Dalhousie University, Canada
2005, BSc Molecular Biology and Genetics, University of Guelph, Canada
Awards
2024 – 2031, Member, Royal Society of Canada College of New Scholars, Artists, and Scientists
2022 – 2023, Top 10 most cited article, EMIR (Johnson & Hug, 2022)
2022, Canadian Society for Microbiologists Thermo Fisher Award
2021, Outstanding Performance Award, University of Waterloo
2021, Ontario Early Researcher Award
2019, Profiled within the Notable Women In Science lamp post banner campaign, Guelph, Ontario
2016 – 2029, Tier II Canada Research Chair in Environmental Microbiology
2015, Kavli Fellow, National Academy of Sciences
2013, Post-Doctoral Fellowship, NSERC
2012, Outstanding Student Poster, American Society for Microbiology General Meeting
2011, Doctoral Completion Award, University of Toronto
2010, Yoshio Masui Prize in Molecular Biology, University of Toronto
2009, Canada Graduate Scholarship D Michael Smith Foreign Study Supplement, NSERC
2008, Governor General’s Gold Medal, Dalhousie University
2007, Helen Sawyer Hogg Graduate Admission Award, University of Toronto
2007, Mary H. Beatty Fellowship, University of Toronto
2007, University of Toronto Fellowship, University of Toronto
2007, Canada Graduate Scholarship D, NSERC
2005, Postgraduate Scholarship M, NSERC
2005, Honorary Pre-Doctoral Scholarship, Killam Foundation
Service
Senior Editor, ISME Communications
Reviewer for Nature, The ISME Journal, Applied and Environmental Microbiology, Environmental Microbiology, BMC Genomics, Microbiome, Bioinformatics, Environmental Science and Technology, FEMS Microbiology Ecology, Frontiers in Environmental Science, Biodegradation, and PLoS ONE (ad hoc)
Professional Associations
American Society for Microbiology (Member)
Canadian Society for Microbiologists (Member)
International Society for Microbial Ecology (Member)
Affiliations and Volunteer Work
2024 – Present, Adjunct Professor, Department of Chemical Engineering and Applied Chemistry, University of Toronto
Waterloo Center for Microbial Research, University of Waterloo (Member)
Water Institute, University of Waterloo (Member)
Teaching*
- BIOL 346 - Microbial Ecology and Diversity
- Taught in 2021, 2022, 2023, 2024, 2026
- BIOL 645 - Recent Advances in Microbial Ecology
- Taught in 2022
* Only courses taught in the past 5 years are displayed.
Selected/Recent Publications
For the full list of Laura Hug's publications, please see Google Scholar.
D. Grégoire, N. George, & L.A. Hug. (2023) Microbial methane cycling in a landfill on a decadal time scale. Nature Communications. 14: 7402 https://doi.org/10.1038/s41467-023-43129-x
L.A. Johnson & L.A. Hug. (2022) Cloacimonadota metabolisms include adaptations in engineered environments that are reflected in the evolutionary history of the phylum. Environmental Microbiology Reports, 14(4): 520-529 https://doi.org/10.1101/2021.10.08.463351
N.A. George, C. Chen, K. Anantharaman, & L.A. Hug. (2025) Discarded diversity: Novel megaphages, auxiliary metabolic genes, and virally encoded CRISPR-Cas systems in landfills. Virology Journal 22: 370 https://doi.org/10.1186/s12985-025-02990-6
M. Chen, D. S. Grégoire, P. St-Germain, C. Berdugo-Clavijo, L.A. Hug. (2025) Microbial diversity and capacity for arsenic biogeochemical cycling in aquifers associated with thermal mobilization. Science of the total environment. 977: 179357 https://doi.org/10.1016/j.scitotenv.2025.179357
L.A. Hug, B.J. Baker, K. Anantharaman, C.T. Brown, A.J. Probst, C.J. Castelle, C. N. Butterfield, A.W. Hernsdorf, Y. Amano, K. Ise, Y. Suzuki, N. Dudek, D.A. Relman, K.M. Finstad, R. Amundson, B.C. Thomas, & J.F. Banfield. (2016) A new view of the tree of life. Nature Microbiology 1: 16048 https://doi.org/10.1038/nmicrobiol.2016.48
In The News
Graduate studies
I am currently seeking to accept graduate students. Please **email me** your resume, and I will review it and respond if interested.