Contact Info
Department of Applied Mathematics
University of Waterloo
Waterloo, Ontario
Canada N2L 3G1
Phone: 519-888-4567, ext. 32700
Fax: 519-746-4319
PDF files require Adobe Acrobat Reader
MC 6460
Nicole Mideo, Department of Ecology & Evolutionary Biology, University of Toronto
Understanding variation in malaria infection dynamics
Infection outcomes are highly variable: some individuals suffer severe illness while others seem relatively unharmed by the same infection. Underlying this variation are numerous sources of heterogeneity, including parasite genetics, host genetics, and infectious dose, among others. Yet mechanistic explanations of differential infection outcomes remain elusive. Focusing on data from experimental malaria infections in lab mice, my research has been developing and refining mathematical models to reveal those mechanistic explanations. In this talk, I will describe what we have learned about the parasite traits, host traits, and their interactions that give rise to the observed variation in malaria infection dynamics and outcomes for hosts.
Contact Info
Department of Applied Mathematics
University of Waterloo
Waterloo, Ontario
Canada N2L 3G1
Phone: 519-888-4567, ext. 32700
Fax: 519-746-4319
PDF files require Adobe Acrobat Reader
The University of Waterloo acknowledges that much of our work takes place on the traditional territory of the Neutral, Anishinaabeg and Haudenosaunee peoples. Our main campus is situated on the Haldimand Tract, the land granted to the Six Nations that includes six miles on each side of the Grand River. Our active work toward reconciliation takes place across our campuses through research, learning, teaching, and community building, and is co-ordinated within the Office of Indigenous Relations.