Pu Chen

Professor, Chemical Engineering; University Research Chair

Research interests: targeted drug and gene delivery; interfacial engineering; bio-medical engineering; polymer synthesis; energy storage and rechargeable batteries

Biography

Professor Chen’s research is at the interface between nanotechnology and biomedicine. It involves the application of physical chemistry, surface thermodynamics, solid state physics, biochemistry and molecular cell biology to biomedical and chemical engineering systems.

At the centre are studies of the molecular self-assembly and interfacial phenomena in multiphase systems where nanomaterials or biomolecules in different states (or phases) co-exist and interact with one another.

The current effort is to design and measure the molecular interaction, nanostructure formation and adsorption kinetics of peptides, DNA, Small Interfering RNA (siRNA), proteins, surfactants and polymers in solution or at interfaces. The research applies techniques emerging from innovations in nanotechnology, genomics, proteomics and nano/microelectronics to problems in nanomedicine, biomaterials, colloid and surface science.

Practical applications include drug and gene delivery; peptide-DNA/RNA binding; protein-lipid interactions, lipid bilayer and cell membrane actions; therapeutic lung surfactants; emulsification, coating, painting, and thin films; surface mass and heat transfer; molecular/microsensors; nanotube membranes and bioseparation; biofuel cells; molecular sensing and nanocellular foaming of polymers.

Chen is a faculty member in the Department of Chemical Engineering at the University of Waterloo.

Education

  • PhD, University of Toronto
  • MASc, University of Toronto
  • MSc, Nanjing University, China
  • BSc, Nanjing University, China

Pu Chen

Research

Research interests

  • Nano-biomedical engineering
  • Colloid and surface science
  • Polymer materials
  • Energy and integrative research
  • Energy storage
  • Rechargeable batteries

Publications

Recent publications include:

  • Wu, Xianwen; Li, Yehua; Li, Chuanchang; He, Zhangxing; Xiang, Yanhong; Xiong, Lizhi; Chen, Doris; Yu, Yan; Sun, Kate; He, Zeqiang; Chen, Pu, The electrochemical performance improvement of LiMn2O4/Zn based on zinc foil as the current collector and thiourea as an electrolyte additive, JOURNAL OF POWER SOURCES, 300, pp453-459, 2015
  • Lu, Sheng; Bennett, W. F. Drew; Ding, Yong; Zhang, Lei; Fan, Helen Y.; Zhao, Danyang; Zheng, Tao; Ouyang, Ping-Kai; Li, Jason; Wu, Yan; Xu, Wen; Chu, Dafeng; Yuan, Yongfang; Heerklotz, Heiko; Karttunen, Mikko; Chen, P., Design and Characterization of a Multifunctional pH-Triggered Peptide C8 for Selective Anticancer Activity, ADVANCED HEALTHCARE MATERIALS, 4(17), pp2709-2718, 2015
  • Pan, Ran; Xu, Wen; Jafari, Mousa; Chen, Baoling; Sheinin, Tatiana; Chen, P. DEGylation Enhanced the Stability of Peptide-siRNA Complexes in Serum, JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 15(12), pp9982-9990, 2015
  • Yuan, Guanghui; Bai, Jintao; The Nam Long Doan; Chen, P. Synthesis and electrochemical properties of LiFePO4/graphene composite as a novel cathode material for rechargeable hybrid aqueous battery, MATERIALS LETTERS, 158, pp248-251, 2015
  • Li, Mingqi; Yu, Yan; Li, Jing; Chen, Baoling; Konarov, Aishuak; Chen, P., Fabrication of graphene nanoplatelets-supported SiOx-disordered carbon composite and its application in lithium-ion batteries, JOURNAL OF POWER SOURCES, 293, pp976-982, 2015
  • Sheikholeslam, M.; Pritzker, M.; Chen, P. Peptide-CNT Hydrogels for Tissue Engineering and Cancer tumor Studies, TISSUE ENGINEERING PART A, 21, ppS223-S224, 2015
  • Mohammadi, M.; Chen, P. Effect of microvascular distribution and its density on interstitial fluid pressure in solid tumors: A computational model, MICROVASCULAR RESEARCH, 101, pp26-32, 2015
  • Pan, Ran; Xu, Wen; Yuan, Feng; Chu, Dafeng; Ding, Yong; Chen, Baoling; Jafari, Mousa; Yuan, Yongfang; Chen, P., A novel peptide for efficient siRNA delivery in vitro and therapeutics in vivo, ACTA BIOMATERIALIA, 21, pp74-84, 2015
  • Dong, Dexian; Chen, Baoling; Chen, P., Bacterial Acclimation Inside an Aqueous Battery, PLOS ONE, 10(6), 2015
  • Sarikhani, K.; Jeddi, K.; Thompson, R. B.; Park, C. B.; Chen, P., Effect of pressure and temperature on interfacial tension of poly lactic acid melt in supercritical carbon dioxide, THERMOCHIMICA ACTA, 609, pp1-6, 2015
  • Chen, Baoling; Xu, Wen; Pan, Ran; Chen, P., Design and characterization of a new peptide vector for short interfering RNA delivery, JOURNAL OF NANOBIOTECHNOLOGY, 13, 2015
  • Sarikhani, K.; Jeddi, K.; Thompson, R. B.; Park, C. B.; Chen, P., Adsorption of Surface-Modified Silica Nanoparticles to the Interface of Melt Poly(lactic acid) and Supercritical Carbon Dioxide, LANGMUIR, 31(20), pp5571-5579, 2015
  • Peng, Zhenhuan; Fang, Wenying; Zhao, Hongbin; Fang, Jianhui; Cheng, Hongwei; The Nam Long Doan; Xu, Jiaqiang; Chen, Pu, Graphene-based ultrathin microporous carbon with smaller sulfur molecules for excellent rate performance of lithium-sulfur cathode, JOURNAL OF POWER SOURCES, 282, pp70-78, 2015
  • Jeddi, Kazem; Sarikhani, Kaveh; Ghaznavi, Mahmoudreza; Zendehboodi, Sohrab; Chen, P., Enhanced cycling performance of a high-energy and low-cost lithium-sulfur battery with a sulfur/hardwood charcoal composite cathode material, JOURNAL OF SOLID STATE ELECTROCHEMISTRY, 19(4), pp1161-1169, 2015
  • Han, Zhixu; Askhatova, Diana; The Nam Long Doan; Hoang, Tuan K. A.; Chen, P., Experimental and mathematical studies on cycle life of rechargeable hybrid aqueous batteries, JOURNAL OF POWER SOURCES, 279, pp238-245, 2015
  • Chu, Dafeng; Xu, Wen; Pan, Ran; Ding, Yong; Sui, Weiping; Chen, P., Rational modification of oligoarginine for highly efficient siRNA delivery: structure-activity relationship and mechanism of intracellular trafficking of siRNA, NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 11(2), pp435-446, 2015
  • Zhang, Yongguang; Zhao, Yan; Gosselink, Denise; Chen, P., Synthesis of poly(ethylene-oxide)/nanoclay solid polymer electrolyte for all solid-state lithium/sulfur battery, IONICS, 21(2), pp381-385, 2015
  • Zhang, Yongguang; Zhao, Yan; Konarov, Aishuak; Li, Zhi; Chen, P., Effect of mesoporous carbon microtube prepared by carbonizing the poplar catkin on sulfur cathode performance in Li/S batteries, JOURNAL OF ALLOYS AND COMPOUNDS, 619, pp298-302, 2015
  • The Nam Long Doan; Hoang, Tuan K. A.; Chen, P., Recent development of polymer membranes as separators for all-vanadium redox flow batteries, RSC ADVANCES, 5(89), pp72805-72815, 2015
  • Hoang, Tuan K. A.; The Nam Long Doan; Sun, Kyung Eun Kate; Chen, P., Corrosion chemistry and protection of zinc & zinc alloys by polymer-containing materials for potential use in rechargeable aqueous batteries, RSC ADVANCES, 5(52), pp41677-41691, 2015
  • Chen, Baoling; Pan, Ran; Askhatova, Diana; Chen, P., Effective small interfering RNA delivery in vitro via a new stearylated cationic peptide, INTERNATIONAL JOURNAL OF NANOMEDICINE, 10, pp3303-3314, 2015
  • Chu, Dafeng; Xu, Wen; Pan, Ran; Chen, P., Co-delivery of drug nanoparticles and siRNA mediated by a modified cell penetrating peptide for inhibiting cancer cell proliferation, RSC ADVANCES, 5(26), pp20554-20556, 2015
  • Xu, Wen; Pan, Ran; Zhao, Danyang; Chu, Dafeng; Wu, Yan; Wang, Rong; Chen, Baoling; Ding, Yong; Sadatmousavi, Parisa; Yuan, Yongfang; Chen, P., Design and Evaluation of Endosomolytic Biocompatible Peptides as Carriers for siRNA Delivery, MOLECULAR PHARMACEUTICS, 12(1), pp56-65, 2015
  • Li, Mingqi; Yu, Yan; Li, Jing; Chen, Baoling; Wu, Xianwen; Tian, Ye; Chen, P., Nanosilica/carbon composite spheres as anodes in Li-ion batteries with excellent cycle stability, JOURNAL OF MATERIALS CHEMISTRY A, 3(4), pp1476-1482, 2015
  • Yuan, Guanghui; Bai, Jintao; The Nam Long Doan; Chen, P., Synthesis and electrochemical investigation of nanosized LiMn2O4 as cathode material for rechargeable hybrid aqueous batteries, MATERIALS LETTERS, 137, pp311-314, 2014
  • Zhang, Yongguang; Zhao, Yan; Bakenov, Zhumabay; Konarov, Aishuak; Chen, P., Preparation of novel network nanostructured sulfur composite cathode with enhanced stable cycle performance, JOURNAL OF POWER SOURCES, 270, pp326-331, 2014
  • Sheikholeslam, M.; Wheeler, S.; Duke, K.; Pritzker, M.; Chen, P., Peptide-Carbon Nanotube Hydrogels as Hybrid Scaffolds for Tissue Engineering, TISSUE ENGINEERING PART A, 20, S113, 2014
  • Zhang, Yongguang; Zhao, Yan; Bakenov, Zhumabay; Tuiyebayeva, Madina; Konarov, Aishuak; Chen, P., Synthesis of Hierarchical Porous Sulfur/Polypyrrole/Multiwalled Carbon Nanotube Composite Cathode for Lithium Batteries, ELECTROCHIMICA ACTA, 143, pp49-55, 2014
  • Naahidi, Sheva; Wang, Yujie; Zhang, Man; Wang, Rong; Jafari, Mousa; Yuan, Yongfang; Dixon, Brian; Chen, P., Evaluation of Biocompatibility of the AC8 Peptide and Its Potential Use as a Drug Carrier, MOLECULAR PHARMACEUTICS, 11(10), pp3409-3420, 2014
  • Sadatmousavi, Parisa; Kovalenko, Eugene; Chen, P., Thermodynamic Characterization of the Interaction between a Peptide-Drug Complex and Serum Proteins, LANGMUIR, 30(37), pp11122-11130, 2014
  • Chen, Yuan; Liu, Yang; Wang, Xin; Li, Kai; Chen, Pu, Preparation of High Purity Crystalline Silicon by Electro-Catalytic Reduction of Sodium Hexafluorosilicate with Sodium below 180 degrees C, PLOS ONE, 9(8), 2014
  • Ghaznavi, Mahmoudreza; Chen, P., Analysis of a Mathematical Model of Lithium-Sulfur Cells Part III: Electrochemical Reaction Kinetics, Transport Properties and Charging, ELECTROCHIMICA ACTA, 137, pp575-585, 2014
  • Konarov, Aishuak; Gosselink, Denise; The Nam Long Doan; Zhang, Yongguang; Zhao, Yan; Chen, P., Simple, scalable, and economical preparation of sulfur-PAN composite cathodes for Li/S batteries, JOURNAL OF POWER SOURCES, 259, pp183-187, 2014
  • Ghaznavi, Mahmoudreza; Chen, P., Sensitivity analysis of a mathematical model of lithium-sulfur cells part I: Applied discharge current and cathode conductivity, JOURNAL OF POWER SOURCES, 257, pp394-401, 2014
  • Ghaznavi, Mahmoudreza; Chen, P., Sensitivity analysis of a mathematical model of lithium-sulfur cells: Part II: Precipitation reaction kinetics and sulfur content, JOURNAL OF POWER SOURCES, 257, pp402-411, 2014
  • Zhang, Yongguang; Bakenov, Zhumabay; Zhao, Yan; Konarov, Aishuak; Wang, Qiang; Chen, P., Three-dimensional carbon fiber as current collector for lithium/sulfur batteries, IONICS, 20(6), pp803-808, 2014
  • Jafari, Mousa; Xu, Wen; Pan, Ran; Sweeting, Chad M.; Karunaratne, Desiree Nedra; Chen, Pu, Serum Stability and Physicochemical Characterization of a Novel Amphipathic Peptide C6M1 for SiRNA Delivery, PLOS ONE, 9(5), 2014
  • Naahidi, Sheva; Jafari, Mousa; Logan, Megan; Edalat, Faramarz; Khademhosseini, Ali; Dixon, Brian; Chen, Pu, Immuno- and hemocompatibility of amino acid pairing peptides for potential use in anticancer drug delivery, JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS, 29(3), pp254-269, 2014
  • Sheikholeslam, M.; Pritzker, M.; Chen, P., Hybrid peptide-carbon nanotube dispersions and hydrogels, CARBON, 71, pp284-293, 2014
  • Li, Jing; Li, Kai; Li, Mingqi; Gosselink, Denise; Zhang, Yongguang; Chen, P., A sulfur-polyacrylonitrile/graphene composite cathode for lithium batteries with excellent cyclability, JOURNAL OF POWER SOURCES, 252, pp107-112, 2014
  • Zhang, Yongguang; Zhao, Yan; Bakenov, Zhumabay; Gosselink, Denise; Chen, P., Poly(vinylidene fluoride-co-hexafluoropropylene)/poly(methylmethacrylate)/nanoclay composite gel polymer electrolyte for lithium/sulfur batteries, JOURNAL OF SOLID STATE ELECTROCHEMISTRY, 18(4), pp1111-1116, 2014
  • Yong, X.; Chen, Y.; Liu, W.; Xu, L.; Zhou, J.; Wang, S.; Chen, P.; Ouyang, P.; Zheng, T., Enhanced cadmium resistance and accumulation in Pseudomonas putida KT2440 expressing the phytochelatin synthase gene of Schizosaccharomyces pombe, LETTERS IN APPLIED MICROBIOLOGY, 58(3), pp255-261, 2014
  • Xu, Wen; Jafari, Mousa; Yuan, Feng; Pan, Ran; Chen, Baoling; Ding, Yong; Sheinin, Tatiana; Chu, Dafeng; Lu, Sheng; Yuan, Yongfang; Chen, P., In vitro and in vivo therapeutic siRNA delivery induced by a tryptophan-rich endosomolytic peptide, JOURNAL OF MATERIALS CHEMISTRY B, 2(36), pp6010-6019, 2014
  • The Nam Long Doan; Gosselink, Denise; Hoang, Tuan K. A.; Chen, P., The effect of sulfur loading on the electrochemical performance of a sulfur-polymer composite cathode coated on aluminium foil, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 16(27), pp13843-13848, 2014
  • The Nam Long Doan; Ghaznavi, Mahmoudreza; Konarov, Aishuak; Zhang, Yongguang; Chen, P., Cyclability of sulfur/dehydrogenated polyacrylonitrile composite cathode in lithium-sulfur batteries, JOURNAL OF SOLID STATE ELECTROCHEMISTRY, 18(1), pp69-76, 2014
  • Kazem Jeddi, Kaveh Sarikhani, Nader Taheri Qazvini, P. Chen, "Stabilizing lithium/sulfur batteries by a composite polymer electrolyte containing mesoporous silica particles," Journal of Power Sources, Volume 245, 1 January 2014.
  • M. Li, K. Li, J. Li, Y. Zhao, Y. Zhang, D. Gosselink and P. Chen, "SiO2/Cu/polyacrylonitrile-C Composite as Anode Material in Lithium Ion Batteries," Journal of Power Sources, Volume 240, 15 October 2013.
  • Yongguang Zhang, Yan Zhao, Zhumabay Bakenov, Moulay-Rachid Babaa, Aishuak Konarov, Cong Ding and P. Chen, "Effect of Graphene on Sulfur/Polyacrylonitrile Nanocomposite Cathode in High Performance Lithium/Sulfur Batteries," Journal of The Electrochemical Society, 160 (8), A1194-A1198 (2013).
  • Y. Zhang, Y. Zhao, A. Konarov, D. Gosselink, H. Soboleski and P. Chen, "A novel nano-sulfur/polypyrrole/graphene nanocomposite cathode with a dual-layered structure for lithium rechargeable batteries," Journal of Power Sources, (2013).
  • T. Doan, M. Ghaznavi, Y. Zhao, Y. Zhang, A. Konarov, M. Sadhu, R. Tagnirala and P. Chen, "Binding mechanism of sulfur and dehydrogenated polyacrylonitrile in sulfur/polymer composite cathode," Journal of Power Sources, 241, 61-19 (2013).
  • M. Jafari, D. Karunaratne, C. Sweeting and P. Chen, "Modification of a Designed Amphipathic Cell Penetrating Peptide and Its Effect on Solubility, Secondary Structure and Uptake Efficiency," Biochemistry, (2013).
  • Kazem Jeddi, Yan Zhao, Yongguang Zhang, Aishuak Konarov and P. Chen, "Fabrication and characterization of an effective polymer nanocomposite electrolyte membrane for high performance lithium/sulfur batteries," Journal of The Electrochemical Society, 160(8), A1052 - A1060 (2013).
  • Yongguang Zhang, Yan Zhao, The Nam Long Doan, Aishuak Konarov, Denise Gosselink, Hayden Greentree Soboleski and P. Chen, "A novel sulfur/polypyrrole/multi-walled carbon nanotube nanocomposite cathode with core-shell tubular structure for lithium rechargeable batteries," Solid State Ionics, 238, 30-35 (2013).
  • Kazem Jeddi, Mahmoudreza Ghaznavi and P. Chen, "A novel polymer electrolyte to improve the cycle life of high performance lithium-sulfur batteries," J. Materials Chemistry A (Communication), 1 (8), 2769 - 2772 (2013).
  • Y. Zhao, Y. Zhang, Z. Bakenov and P. Chen, "Electrochemical Performance of Lithium Gel Polymer Battery with Nanostructured Sulfur/Carbon Composite Cathode," Solid State Ionics, 234, 40-45 (2013).
  • Sheva Naahidi, Mousa Jafari, Faramarz Edalat, Kevin Raymond, Ali Khademhosseini and P. Chen, "Biocompatibility of Engineered Nanoparticles for Drug Delivery," J. Controlled Release, 166, 182-194 (2013).
  • Y. Kim, C. Park, P. Chen and R. Thompson, "Maximal cell density predictions for compressible polymer foams," Polymer, 54, 841-845 (2013).
  • Yongguang Zhang, Zhumabay Bakenov, Yan Zhao, Aishuak Konarov, The Nam Long Doan, Kyung Eun Kate Sun, Assiya Yermukhambetova, P. Chen, "Effect of nanosized Mg0.6Ni0.4O prepared by self-propagating high temperature synthesis on sulfur cathode performance in Li/S batteries,Powder Technology, 235, 248-255(2013).
  • Yongguang Zhang, Yan Zhao, Assiya Yermukhambetova, Zhumabay Bakenov and P. Chen, "Ternary sulfur/polyacrylonitrile/Mg0.6Ni0.4O composite cathode for high performance lithium/sulfur batteries,"J. Mater. Chem. A, 1 (2), 295-301(2013).
  • Kazem Jeddi, Nader Taheri Qazvini, Daniele Cangialosi, P. Chen, "Correlation Between Segmental Dynamics, Glass Transition, and Lithium Ion Conduction in Poly(Methyl Methacrylate)/Ionic Liquid Mixture, " Journal of Macromolecular Science, Part B: Physics (accepted, 2012) 52:590-603, 2013.
  • M. Jafari, W. Xu, S. Naahidi, B. Chen and P. Chen, "A New Amphipathic, Amino Acid Pairing (AAP) Peptide as Sirna Delivery Carrier: Physicochemical Characterization and in vitro Uptake Studies," The Journal of Physical Chemistry B, 116, 13183-13191 (2012).
  • A. Sheikholeslam, M. Pritzker and P. Chen, "Dispersion of multi-walled carbon nanotubes in water using ionic-complementary peptides," Langmuir, 28, 12550-12556 (2012).
  • Y. Wang, S.A. Shakhshir, X. Li and P. Chen, "Superhydrophobic Flow Channel Surface and its Impact on PEM Fuel Cell Performance," International Journal of Low-Carbon Technologies, (accepted, 2012).
  • W. Ma, S. Lu, P. Pan, P. Sadatmousavi, Y. Yuan and P. Chen, "Parmacokinetics of Peptide Mediated Delivery of Anticancer Drug Ellipticine," PLoS ONE, (accepted, 2012).
  • J. Yan, J. Wang, H. Liu, Z. Bakenov, D. Gosselink, P. Chen, "Rechargeable Hybrid Aqueous Batteries," Journal of Power Sources (Short Communication), 216, 222-226 (2012).
  • P. Sadatmousavi, T. Mamo and P. Chen, "Diethylene Glycol (DEG) Functionalized Self-Assembling Peptide Nanofibers and their Hydrophobic Drug Delivery Potential," Acta Biomaterialia, 8, 3241-3250 (2012).
  • Yan Wu, Parisa Sadatmousavi, Rong Wang, Sheng Lu, Yongfang Yuan, P. Chen, "Self-assembling peptide-based nanoparticles enhance anticancer effect of ellipticine in vitro and in vivo," International Journal of Nanomedicine, 7, 3221-3233 (2012).
  • Madjid Soltani and P. Chen, "Effect of tumor shape and size on drug delivery to solid tumors," Journal of Biological Engineering, 6:4 (2012). (doi:10.1186/1754-1611-6-4) (Top ten most accessed article, May 2012).
  • Y. Zhao, Y. Zhang, D. Gosselink, T.N.L. Doan, M. Sadhu, H. Cheang and P. Chen, "Polymer electrolytes for lithium/sulfur batteries," Membranes, 2, 553-564 (2012).
  • S. Lu, H. Wang, Y. Sheng, M. Liu and P. Chen, “Molecular Binding of Self-assembling Peptide EAK16-II with Anticancer Agent EPT and its Implication in Cancer Cell Inhibition,” J. Controlled Release, (accepted, 2012).
  • Y. Zhang, Z. Bakenov, Y. Zhao, A. Konarov, T. Doan, M. Malik, T. Paron and P. Chen, “One-step synthesis of branched sulfur/polypyrrole nanocomposite cathode for lithium rechargeable batteries,” Journal of Power Sources, 208, 1-8 (2012).
  • M. Jafari, M. Soltani, S. Naahidi, D.N. Karunaratne and P. Chen, “Nonviral approach for targeted nucleic acid delivery,” Current Medicinal Chemistry, 19, 197-208 (2012).
  • A. Firooz and P. Chen, “Surface Tension and Adsorption Kinetics of Amphiphiles in Aqueous Solutions: the Role of Carbon Chain Length and Temperature,” Journal of Colloid & Interface Science, 370, 183-191 (2011).
  • A. Firooz and P. Chen, “Impact of Carbon Dioxide on the Surface Tension of 1-hexanol Aqueous Solutions,” Colloids and Surfaces A: Physicochem. & Eng. Aspects, 392, 355-364 (2011).
  • Y. Kim, C. Park, P. Chen and R. Thompson, “Towards Maximal Cell Density Predictions for Polymeric Foams,” Polymer, 52, 5622-5629 (2011).
  • X. Ouyang, P. Zhang, X. Qiu, Y. Deng and P. Chen, “Lignosulfonate Separation using Gel Column Chromatography,” Ind. Eng. Chem. Res., 50, 10792-10799 (2011). (dx.doi.org/10.1021/ie200975e).
  • I.H. Mustafa, A. Elkamel, P. Chen, G. Ibrahim, “Effect of Cholineacetyltransferase Activity and Choline Recycle Ratio on Diffusion-Reaction Modelling, Bifurcation and Chaotic Behavior of Acetylcholine Neurocycle and their Relation to Alzheimer's and Parkinson's Diseases,” Chemical Engineering Science, 68, 19-35 (2011).
  • P. Chen and X. Kan, “Nanostructured Materials for Rechargeable Lithium Batteries,” Editorial, The Open Materials Science Journal, 5, 203 (2011).
  • H. Tao, Z. Feng, H. Liu, X. Kan and P. Chen, “Reality and Future of Rechargeable Lithium Batteries,” The Open Materials Science Journal, 5, 204-214 (2011).
  • Y. Zhang, Y. Zhao, K.E. Sun and P. Chen, “Development in Lithium/Sulfur Secondary Batteries,” The Open Materials Science Journal, 5, 215-221 (2011).
  • Y. Kim, C.B. Park, P. Chen and R.B. Thompson, “Origins of the Failure of Classical Nucleation Theory for Nanocellular Polymer Foams,” Soft Matter, 7(16), 7351-7358 (2011).
  • M. Soltani and P. Chen, “Numerical Modeling of Fluid Flow in Solid Tumors,” PLoS ONE, (accepted, 2011).
  • Y. Sheng, W. Wang and P. Chen, “Peptide Adsorption on the Hydrophobic Surface: A Free Energy Perspective,” J. Molecular Structure, (accepted, 2011).
  • S. Fung, H. Yang, P. Sadatmousavi, Y. Sheng, T. Mamo, R. Nazarian and P. Chen, “Amino Acid Pairing for De Novo Design of Self-Assembling Peptides and their Drug Delivery Potential,” Adv. Funct. Mater., 21, 2456-2464 (2011).
  • Abdolhamid Firooz, and P. Chen, " Effect of Temperature on the Surface Tension of 1-Hexanol Aqueous Solutions", Langmuir, (accepted, 2011)
  • P. Sadatmousavi, M. Soltani, R. Nazarian, T. Mamo, S. Lu, J. Wang, W. Xu, M. Jafari and P. Chen, "Design Principles of Self-Assembling Peptides and their Potential Applications," Comprehensive Biotechnology, 2nd edition, M. Moo-Young, ed., Elsevier, Oxford, UK, (accepted, 2010).
  • R.B. Thompson, C.B. Park and P. Chen, “Reduction of polymer surface tension by crystallized polymer nanoparticles,” J. Chem. Phys., (accepted, 2010)
  • P. Sadatmousavi, M. Soltani, R. Nazariann, M. Jafari and P. Chen, “Self-assembling peptides: potential role in tumor targeting,” Current Pharmaceutical Biotechnology, (accepted, 2010)
  • Y. Sheng, W. Wang and P. Chen, “Interaction of an ionic complementary peptide with a hydrophobic graphic surface,” Protein Science, (accepted, 2010)
  • S. Lu and P. Chen, “Constructing Biomaterials using Self-assembling Peptide Building Blocks,” Frontiers of Materials Science, 4(2), 145-151 (2010)
  • A. Prpich, Y. Sheng, W. Wang, E. Biswas and P. Chen, “Tension at the surface: which phase is more important, liquid or vapor?” PLoS ONE, 4(12): e8281, 1-6 (2009)
  • D. Zou, Z. Tie, C. Lu, M. Qin, X. Lu, M. Wang, W. Wang, and P. Chen, “Effects of Hydrophobicity and Anions on Self-Assembly of the Peptide EMK16-II,” Biopolymers, 93 (4), 318-329 (2010)
  • Y. Sheng, W. Wang and P. Chen, “Adsorption of an Ionic-Complementary Peptide on the Hydrophobic Graphite Surface,” J. Physical Chemistry C, 114, 454-459 (2010)
  • Z. Qian, M. Khan, S. Mikkelsen and P. Chen, “Improved Enzyme Immobilization on an Ionic-complementary Peptide Modified Electrode for Biomolecular Sensing,” Langmuir, 26 (3), 2176-2180 (2010)
  • H. Wei, R. Thompson, C. Park and P. Chen, “Surface Tension of High Density Polyethylene (HDPE) in Supercritical Nitrogen: Effect of Polymer Crystallization,” Colloids and Surfaces A: Physicochem. & Eng. Aspects, 354, 347-352 (2010)
  • M. Jafari and P. Chen, “Peptide mediated siRNA delivery,” Current Topics in Medicinal Chemistry, 9, 1088-1097 (2009)
  • H. Yang, S. Fung, M. Pritzker and P. Chen, “Ionic-Complementary Peptide Matrix for Enzyme Immobilization and Biomolecular Sensing,” Langmuir (Letters), 25 (14), 7773-7777 (2009)
  • Hyder M.N.; Chen P., "Pervaporation Dehydration of Ethylene Glycol with Chitosan-Poly(vinyl alcohol) Blend Membranes: Effect of CS-PVA Blending Ratios," J. Membrane Sci., 340, 171-180 (2009)
  • Firooz A.; Chen P., "Surface tension response to surface perturbation of a volatile amphiphilic organic solution", book chapter, IAENG Transactions on engineering technologies volume II, American Institute of Physics, Chap.6, 50-61  (2009).
  • Hyder M.N.; Huang R.Y.M. ; Chen P., "Composite Poly(vinyl alcohol)-Poly(sulfone) Membranes crosslinked by Trimesoyl Chloride: Characterization and Dehydration of Ethylene Glycol-Water Mixtures," J. Membrane Sci., 326, 363-371 (2009).
  • Mustafa I.; Ibrahim G.; Elkamel A.; Elnashaie S; Chen P., “Non-Linear Feedback Modeling and Bifurcation of the Acetylcholine Neurocycle and its Relation to Alzheimer's and Parkinson's Diseases,” Chemical  Engineering Sci., 64, 69 (2009).
  • Hyder M.N.; Huang R.Y.M. ; Chen P., "Pervaporation Dehydration of Alcohol-Water Mixtures: Optimization for Permeate Flux and Selectivity by Central Composite Rotatable Design(CCRD)" J. Membrane Sci., 326, 343-353 (2009).
  • Biswas M.E.; Prpich A.M.; Chatzis I.; Chen P., “Studies of dynamic surface tension of polyoxyethylene alkylphenols at the air–water interface,” Colloids and Surfaces A: Physicochem. & Eng. Aspects, 330, 213 (2008)
  • Thompson R.B.; Macdonald J.R.; Chen P., “Origins of Change in Molecular Weight Dependence for Polymer Surface Tension,” Phys. Rev. E. Rapid Communications, 78, 030801 (R) (2008). (Also in the October 1, 2008 issue of Virtual Journal of Biological Physics Research.)
  • Firooz A.; Chen P., "Effect of Surface Expansion and Compression on the Surface Tension of 1-octanol Solutions", Engineering Letters, IAENG, 16, 4, 562-567, (2008).
  • Fung S. Y.; Yang H.; Bhola P.T.; Sadatmousavi P.; Muzar E.; Liu M.; Chen P., " Self-Assembling Peptide as a Potential Carrier for Hydrophobic Anticancer Drug Ellipticine: Complexation, Release and In Vitro Delivery",  Adv. Funct. Mater. 18, 1-10, (2008).
  • Law M.; Jafari M.; Chen P., "Physicochemical Characterization of SiRNA-peptide Complexes",  Biotechnology Progress, 24, 957-963, (2008).
  • Yang H.; Fung S.; Pritzker M.; Chen P., "Mechanical Force-Induced Peptide Assembly at Liquid/Solid Interfaces," Angew. Chem. Int. Ed., (also Angewandte Chemie) 120, 4469-4472 (2008).
  • Fung S.; Yang H. ; Chen P., "Sequence Effect of Self-Assembling Peptides on the Complexation and In-Vitro Delivery of the Hydrophobic Anticancer Drug Ellipticine," PLoS ONE, 3(4): e1956 (2008).
  • Yang H. ; Fung S.; Sun W. ;  Mikkelsen S. ; Pritzker M. ; Chen P., "Ionic-Complementary Peptide Modified HOPG Electrode for Biosensor Application," Biotech. Prog.24, 964 (2008).
  • Hyder M.N.; Huang R.Y.M.; Chen P., "Effect of Selective Layer Thickness on Pervaporation of Composite Poly(vinyl alcohol)-Poly(sulfone) Membranes," J. Membrane Sci., 318, 387-396 (2008).
  • Yang H. ; Fung S.; Pritzker M. ;  Chen P., "Modification of Hydrophilic and Hydrophobic Surfaces Using an Ionic-Complementary Peptide," PLoS ONE, 2 (12): e1325, 1-11 (2007).
  • Prpich A. ; Biswas M.E. ;  Chen P. , "Adsorption Kinetics of Aqueous n-Alcohols: A New Kinetic Equation for Surfactant Transfer," J. Phys. Chem. C., 112, 2522-2528 (2007).
  • Wang M. ; Adikane H.V. ; Duhamel J. ; Chen P., "A Quantitative Study of the Complexation of a Self-Assembling Peptide with Oligodeoxynucleotides," Biophysical J., 93, 2477-2490 (2007).
  • Yang H. ; Fung S.; Pritzker M. ;  Chen P., "Surface-Assisted Assembly of an Ionic-Complementary Peptide: Controllable Growth of Nanofibers," J. Am. Chem. Soc., 129, 12200-12210 (2007).
  • Park, H.;  Tzoganakis, C.; Park, C.B.; Chen, P., "Effect of Molecular Weight on the Surface Tension of Polystyrene in Supercritical Nitrogen," Industrial & Engineering Chemistry Research, 46, 3849-3851 (2007).
  • Wang M. ; Adikane H.V. ; Duhamel J. ; Chen P., "Protection of Oligodeoxynucleotides against Nuclease Degradation through Association with Self-Assembling Peptides," Biomaterials, 29, 1099-1108 (2007).
  • Park, H.; Thompson, R.B.; Lanson, N.; Tzoganakis, C.; Park, C.B.; Chen, P., "Effect of Temperature and Pressure on Surface Tension of Polystyrene in Supercritical Carbon Dioxide,"  J. Phys. Chem. B., 111, 3859 ( 2007).
  • Fung S.; Yang H.; Chen P., "Formulation of Colloidal Suspension of Hydrophobic Compounds using an Amphiphilic Self-Assembling Peptide," Colloids and Surfaces B: Biointerfaces, 55, 200 (2007).
  • Hyder, M.N.;  Huang, R.Y.M.;  Chen, P., "Correlation of physicochemical characteristics with pervaporation performance of poly(vinyl alcohol) membranes ",  J. of Membrane Sci., 283, 281, (2006).
  • Long J.; Chen P., "On the Role of Energy Barriers in Determining Contact Angle Hysteresis," Adv. Colloid  Interface Sci., 127, 55 (2006).
  • Yang, H.; Pritzker, M.; Fung, S.Y.; Sheng, Y.; Wang W.; Chen P., "Anion effect on the nanostructure of a metal ion binding self-assembling peptide." Langmuir, 22, 8556 (2006)
  • Fung, S.Y.; Duhamel, J.; Chen, P., "Solvent effect on the photophysical properties of the anticancer agent ellipticine." J. Phys. Chem. A 110, 11446, (2006).
  • Park, H.; Park, C.B.; Tzoganakis, C.; Tan, K.H. and Chen, P., “Surface Tension Measurement of Polystyrene Melts in Supercritical Carbon Dioxide,” Industrial & Engineering Chemistry Research, 45, 1650 (2006).
  • Svang-Ariyaskul A.;  Huang R.Y.M.; Douglas P.L.; R. Pal, Feng X.; Chen P.; Liu L., "Blended chitosan and polyvinyl alcohol membranes for the pervaporation dehydration of isopropanol," J. Membrane Sci., 280, 815 (2006)
  • Ouyang X.; Qiu X.; Chen P., "Physicochemical Characterization of Calcium Lignosulfonate-A Potentially Useful Water Reducer," Colloids and Surfaces A: Physicochem. Eng. Asp., 282, 489 (2006).
  • Long, J.; Hyder, M.N.;  Huang, R.Y.M. ;  Chen, P., "Thermodynamic modeling of contact angles on rough, heterogeneous surfaces", Adv. in Colloid and  Interfaces Science, 118, 173 (2005).
  • Biswas, M.E., Chatzis, I., Ioannidis, M.A., and Chen, P., “Modelling of adsorption dynamics at air-liquid interfaces: Statistical Rate Theory (SRT),” J. of Colloid and Interface Sci., 286, 14 (2005).
  • Shao, P.; Ji, G.; Chen, P., Gold nanotube membranes: Preparation, characterization and application for enantioseparation, J. of Membrane Sci., 255, 1, (2005).
  • Jun, S.; Hong, Y.; Imamura, H.; Ha, B.-Y.; Bechhoefer, J.; Chen, P., “Self-assembly of the ionic peptide EAK16: The effect of charge distributions on self-assembly.”  Biophysical J., 87, 1249 (2004).
  • Hong, Y.; Lau, L. S.; Legge, R. L.; Chen, P.,  “Critical self-assembly concentration of an ionic-complementary peptide EAK16-I.” J. of Adhesion, 80, 913 (2004).
  • Keyes-Baig, C.; Duhamel, J.; Fung, S-Y; Bezaire, J.; Chen, P., “Self-Assembling Peptide as a Potential Carrier of Hydrophobic Compounds.”  J. of the Am. Chem. Soc., 126 (24), 7522 (2004).
  • Mak, C.; Cornu, E.; Moresoli, C.; Chen, P., “Surface tension, diffusion and kinetics studies of an air-stripping process.” Separation and Purification Technology,  36(2),  95 (2004).
  • Long, J.; Tzoganakis, C.; Chen, P., “Surface characteristics of hydrosilylated polypropylenes: effect of Co-catalyst and reaction temperature.”  Polymer Engineering and Sci., 44(1), 56(2004).
  • Xue, A.; Tzoganakis, C.; Chen, P.., “Measurement of interfacial tension in PS/LDPE melts saturated with supercritical CO2.” Polymer Engineering and Sci.,  44(1),  18-27 (2004).
  • Hong Y.; Legge, R. L.; Zhang, S.; Chen, P., “Effect of Amino Acid Sequence and pH on Nanofiber Formation of  Self-Assembling Peptides EAK16-II and EAK16-IV.”  Biomacromolecules, 4(5), 1433(2003).
  • Yang, L., Biswas, M.E., and Chen, P., “Study of Binding between Protein A and Immunoglobulin G using a Surface Tension Probe,” Biophysical J., 84, 509 (2003).
  • Dhadwar, S. S.; Bemman, T.; Anderson, W. A.; Chen, P., “Yeast cell adhesion on oligopeptide modified surfaces.” Biotechnology Advances, 21(5), 395 (2003).
  • Fung, S. Y.; Keyes, C.; Duhamel, J.; Chen, P., “Concentration effect on the aggregation of a self-assembling oligopeptide,” Biophysical J., 85(1), 537-548 (2003).
  • Xia, F.; Gray, W. G.; Chen, P., “Thermodynamic fundamental equation of contact lines: selection of independent variables.” J. of Colloid and Interface Science, 261(2), 464  (2003).
  • Long, J.; Tzoganakis, C.; Chen, P., “Surface characteristics of hydrosilylated polypropylene.” J. of Applied Polymer Sci., 88(14), 3117 (2003).
  • Xia, F.; Chen, P., “An image analysis program for measuring contact angles of arbitrary drop shape.”, J. of  Imaging Science and Technology,  47(1),  44-53 (2003).
  • Long J.; Tzoganakis, C.; Chen, P.., “Surface characterization of hydro-silylated polypropylene.”  Annual Technical Conference - Society of Plastics Engineers, 60th(Vol. 3),  2772 (2002).
  • Yang, L.; Chen, P., “Chitosan/coarse filter paper composite membrane for fast purification of IgG from human  serum.“ J. of Membrane Sci.,  205(1-2),  141 (2002).
  • Yang L. , Hsiao W.W. and  Chen P., "Chitosan-Cellulose Composite Membrane for Affinity Purification of Biopolymers and Immunoadsorption," J. Membrane Sci., 197, 185 (2002).
  • Long J. ;  Chen P., "Surface Characterization of Hydrosilylated Polypropylene: Contact Angle Measurement and Atomic Force Microscopy", Langmuir, Vol. 17, p. 1965 (2001).
  • Chen, P., “Understanding the dynamic surface tension of solutions containing volatile organic compounds (VOCs).”  Colloids and Surfaces, A: Physicochemical and Engineering Aspects, 192(1-3), 195 (2001).
  • Long J.;  Chen P., "Modeling of Concentrated Suspension Flow -- Bi-Disperse System", Transaction of the  Canadian Society for Mechanical Engineering, Vol. 24 (No. 1B), p. 151 (2000).
  • Chen P., "The Line Adsorption Equation: The One-Dimensional Counterpart of the Gibbs Adsorption Equation," Colloids Surfaces A: Physicochem. Eng. Aspects, 161, p. 23 (2000).

Please see Pu Chen's Google Scholar profile for a current list of his peer-reviewed articles.

Contact