Contact Waterloo Institute for Nanotechnology
Mike & Ophelia Lazaridis Quantum-Nano Centre, Room 3606
University of Waterloo
200 University Ave. W.
Waterloo, ON. N2L 3G1
+1 519 888 4567, ext.38654
Research interests: MEMS optical scanners; CNT sensors; LOC designs
As Canada Research Chair in Micro and Nanodevices, Professor John T.W. Yeow is developing nanodevices (machines that work on a molecular level) and highly selective sensors that will help create new medical instruments for diagnosing and treating disease.
Bringing together knowledge and technology from chemistry and from materials and chemical engineering labs, Yeow will design, develop, manufacture, and test a miniaturized catheter device for in vivo, or internal, body imaging. This device will allow physicians to examine small and previously unseen human cavities, and assist in the early detection of diseases such as cancer.
Yeow is also developing miniature radiation instruments and sensors for cancer treatment that will allow for a more focused, yet less invasive, delivery of radiation treatment, as well as real-time measurement of the delivered dose during radiation therapy.
Ultimately, Yeow’s research will improve patients’ quality-of-life through the early detection of disease and the development of more effective treatment. In this translational research, the technologies developed will find applications in areas beyond biomedical applications.
- PhD, Mechanical and Industrial Engineering, University of Toronto
- MASc, Mechanical and Industrial Engineering, University of Toronto
- BASc, University of Toronto
Awards and Honours
|Year||Awards and Honours|
|2015||Fellow of the Engineering Institute of Canada (EIC)|
|2008||Young Engineering Award, PEO|
Micro-/Nano-Electro Mechanical Systems
Micro/Nanoelectromechanical Systems (MEMS/NEMS) provide the advantages of small size, low cost, low power consumption, low mass, high reliability, and low maintenance on both the system as well as the component levels. My research interests are to develop and fabricate mechanical machines that are integrated with microelectronics at the micron scale. New device concepts include but are not limited to: the integration of micro-optics components, miniature signal processing devices, biomedical/genome processing devices, miniature electromechanical wireless components (filters, mixers, antennas), miniature opto-electromechanical devices (optical cross connect, optical relays, optical multiplexers, deformable optics), miniature biosensors and environmental sensors, and microfluidics devices. Issues such as self-testing, self-assembly, and automated packaging will be explored.
Like the Integrated Circuits (IC) fabrication, the fabrication process of MEMS is inherently planar. Three-dimensional (3-D) mechanical structures are built by the successive deposition and etching of structural and sacrificial layers of silicon-based materials in the same plane. Therefore, only simple in-plane structures can be constructed. The planar fabrication process limits the designs, functionality, and applications of current MEMS devices. Therefore, the ability to assemble micro parts by robotic micromanipulators would have serious implications. MEMS components such as out-of-plane gears, actuators, cantilevers, sensors, and end-effectors can be assembled. In the world with micro-assembly, micro parts are no longer restricted to 2 or 3 Degree-of-Freedom (DoF) motion. Multiple DoF micro components will not only enhance the performance and capability of MEMS, but also create new market for the technology.
Nanodevices for Biomedical Applications
On a smaller scale, the potential applications of Carbon Nanotubes (CNT) for biomedical instruments are limitless. CNT exhibit unique properties that include extremely high mechanical strength, high thermal conductivity, excellent chemical and thermal stability. My nanotechnology research thrust will focus on developing novel designs and fabrication concepts based on CNT/nanotechnology for next-generation instruments. The ultimate goal of the research is to realize fully functioning performance-enhanced biomedical nanodevices for clinical deployment.
- MEMS optical scanner for endoscopic optical coherence tomographic imaging
- Micromirror devices for genetic microarray reading and tissue imaging
- Robotics for micromanipulations of MEMS components
- Carbon nanotube-based sensors for biomedical applications
- Lab-on-a-chip designs
- M. Ahmadi, E. Osei, J. Yeow, Bacteriorhodopsin for Superficial X-ray Sensing, Sensors & Actuators: B. Chemical, (accepted- in press).
- Mehdi Shahini, John Yeow, “Carbon nanotube for voltage reduction and throughput enhancement of electrical cell lysis on a lab-on-a-chip”, Nanotechnology, Vol. 22 (32), 2011
- Bai, Y., Pallapa, M., Chen, A., Constantinou, P., Damaskinos, S., Wilson, B. and Yeow, J. A 2D MEMS mirror with sidewall electrodes applied for confocal MACROscope imaging, Journal of Microscopy, (2011)
- W. Wan, J.T.W. Yeow, "Integration of Nanoparticle Cell Lysis and Microchip PCR for One-Step Rapid Detection of Bacteria," Biomedical Microdevices (in press)
- J. Orchard, J.T.W. Yeow, "Toward a Flexible and Portable CT Scanner," The Open Medical Imaging Journal (in press)
- L. L. P. Wong, A. I. Chen, A. S. Logan, and J. T. W. Yeow, "An FPGA-Based Ultrasound Imaging System Using Capacitive Micromachined Ultrasonic Transducers," IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, (in press)
- A. S. Logan, L. L. P. Wong, and J. T. W. Yeow, “A 1-D Capacitive Micromachined Ultrasonic Transducer Imaging Array Fabricated with a Silicon-Nitride-Based Fusion Bonding Process,” IEEE/ASME Transactions on Mechatronics, vol. 16, no. 5, pp. 861-865, Oct. 2011.
- W. Sun, J. T. W. Yeow, Z. Sun, Output-error-constrained tracking control of an electrostatic microelectromechanical system beyond the pull-in limit, IET Proceedings-Control Theory and Applications, (in press)
- A. Carty, J.T.W. Yeow, “WIN: Breaking New Ground in Nanotechnology at Waterloo,” IEEE Nanotechnology Magazine, (in press)
- Mohsen Shahini, William Melek, John Yeow, "Automated sequential manipulation of micro objects by using adaptive controller" (submitted to Journal of Micromechanics and Microengineering)
- S. Nambiar and J. T. W. Yeow, "Conductive polymer-based sensors for biomedical applications", Biosensors and Bioelectronics, 26(5), 1825-1832, 2011
- A. Logan, L. Wong, A. I. Chen and J. T. W. Yeow, “A 32x32 Element Row-Column Addressed Capacitive Micromachined Ultrasonic Transducer,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 58, no. 6, pp. 1266-1271, June 2011.
- Weijie Wan and John T.W. Yeow Study of a novel cell lysis method with titanium dioxide for Lab-on-a-Chip devices, Biomedical Microdevices, DOI: 10.1007/s10544-011-9521-y, 2011
- Morteza Ahmadi, John T.W. Yeow, Fabrication and Characterization of a Radiation Sensor Based on Bacteriorhodopsin. Biosensors and Bioelectronics, Volume 26, pp 2171-2176, 2011
- M. Shahini, W.W. Melek, J.T.W. Yeow, “Characterization of surface micro forces under varying operational condition in micro-sized object pushing: An empirical approach,” Journal of Micromechanics and Microengineering (in press)
- Yun Wang, Seungwoo Park, John Yeow, Andreas Langner and Frank Müller, A capacitive humidity sensor based on ordered macroporous silicon with thin film surface coating, Sensors & Actuators: B. (In press)
- X. Gao, Q.S. Kang, J.T.W. Yeow, R Barnett, “Design and evaluation of quantum dot sensors for making superficial x-ray energy radiation measurements,” Nanotechnology, vol. 21, 285502, 2010.
- Yanhui Bai, John T.W. Yeow, Paul Constantinou, Savvas Damaskinos,and Brian C.Wilson, “A 2-D micromachined SOI MEMS mirror with sidewall electrodes for biomedical imaging”, IEEE/ASME Transactions on Mechatronics (Focused Section on Optomechatronics), Mar. 2010 (In press)
- Yanhui Bai, John T.W. Yeow, and Brian C. Wilson “Design,fabrication, and characteristics of a MEMS micromirror with sidewall electrodes”, IEEE Journal of Microelectromechanical Systems, Vol.19, No. 3, pp619-631, June 2010.
- W.Wan, J.T.W. Yeow, “Effect of gold nanoparticles with different sizes on polymerase chain reaction efficiency,” Nanotechnology, 20, 325702, 2009.
- M. Shahini, W. Melek, J. Yeow, "Micro force compensation in automated micro object positioning using adaptive neural networks," Smart Materials and Structures, vol. 18, no. 9, 2009
- James T. Y. Lin, John T. W. Yeow and Weijie Wan, "Controlling Two-Dimensional Movement of Microparticles over an Electrode Array Surface," Biomedical Microdevices (2009) 11:193–200.
- Yun Wang, John Yeow, "A Review of Carbon Nanotubes Based Gas Sensors" , Journal of Sensor, Article ID 493904, 2009.
- A. Logan and J. T. W. Yeow, “Fabricating capacitive micromachined ultrasonic transducers with a novel silicon-nitride based wafer bonding process,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 56, no. 5, pp. 1074–1084, 2009.
- Yun Wang, John Yeow, "Humidity Sensing of Ordered Macroporous Silicon with HfO2 Thin Film Surface Coating" , IEEE Sensors Journal, Vol. 9, 541-547, 2009.
- A.A. Alzaydi, J.T.W. Yeow, S.L. Lee*, “Hydraulic Controlled Polyester-Based Micro Adaptive Mirror with Adjustable Focal Length,” Mechatronics, vol. 18, no. 2, pp. 61-70, 2008.
- J. Orchard, J.T.W. Yeow, “Toward a Flexible and Portable CT Scanner, “Medical Image Computing and Computer-Assisted Intervention – Lecture Notes in Computer Science, vol. 5242/2008, pp. 188-195, 2008.
- Sangtak Park, So-Ra Chung and John T.W. Yeow, "Design and Analysis of Stacked Micromirrors in Stacked Conofigurations with Moving Electrodes", International Journal of Smart Sensing and Intelligent System, vol. 1, no. 2, June 2008
- J. Ma, J.T.W. Yeow, J.C.L. Chow, R.B. Barnett, “A Carbon Fiber Based Radiation Sensor for Dosimetric Measurement in Radiotherapy,” Carbon, vol. 46, no. 14, pp. 1869-1873, 2008
- Sangtak Park, So-Ra Chung, and John T. W. Yeow, "A Design Analysis of Micromirrors in Stacked Configurations with Moving Electrodes," International Journal of Smart Sensing and Intelligent Systems, Vol.2: 480-497, 2008
- D. Roy Mahapatra, N. Sinha, J.T.W. Yeow and R.V.N. Melnik, "Field Emission from Strained Carbon Nanotubes on Cathode Substrate," Applied Surface Science. vol. 5, no. 1, pp. 1959-1966.
- Y.H. Bai, T.W.Yeow, B.C. Wilson, "A characteristic study of micromirror with sidewall Electrodes", International Journal of Optomechatronics, vol.1, no.3, pp.231-258, 2007
- J. T. Y. Lin and J.T.W. Yeow,"Enhancing dielectrophoresis effect through novel electrode geometry," Biomedical Microdevices, Volume 9, Number 6, December 2007, 823-831
- N. Sinha, D.R. Mahapatra, Y. Sun, J.T.W. Yeow, R. Melnik, and D.A. Jaffray, "Electro-mechanical interactions in carbon nanotube based thin film field emitting diode," Nanotechnology (Accepted)
- N. Sinha, D.R. Mahapatra, J.T.W. Yeow, R.V.N. Melnik, and D.A. Jaffray, “Carbon nanotube thin film field emitting diode: understanding the system response based on multiphysics modeling,” Journal of Computational and Theoretical Nanoscience, vol. 4, no. 3, pp. 535-549, 2007.
- S.S. Abdallah, J.T.W. Yeow, “ZL-Switching matrix: An optimal scalable free-Space strictly nonblocking 2D OXC architecture,” Journal of Optical Networking (accepted)
- J.D. Yantzi, J.T.W. Yeow, S.S. Abdallah, “Multiphase Electrodes for Microbead Control Applications: Integration of DEP and Electrokinetics for Bio-Particle Positioning,” Biosensors and Bioelectronics (accepted)
- J. Ma, J.T.W. Yeow, J.C.L. Chow, R.B. Barnett, “A Carbon Nanotube-based Radiation Sensor,” special issue on Biomedical Robotics and Biomedical Mechatronics for the International Journal of Robotics and Automation (accepted)
- J. Ma, J.T.W. Yeow, J.C.L. Chow, and R.B. Barnett, A Customized Radiation Sensor for Ionization Collection. To appear in IEEE Sensors Journal, December 2006.
- J.T.W. Yeow, J.P.M. She, “Carbon nanotube-enhanced capillary condensation for capacitive humidity sensor,” Nanotechnology 17, pp. 5441-5448, 2006.
- J.P.M. She, J.T.W. Yeow, Nanotechnology-Enabled Wireless Sensor Networks: From A Device Perspective, To appear in April issue, IEEE Sensors Journal, 2006
- N. Sinha, J. Ma, and J. T.W. Yeow, Carbon Nanotube Based Sensors, Journal of Nanoscience and Nanotechnology, Vol. 6, No. 3, pp. 573-590, 2006.
- J.T.W. Yeow, S. Abdallah, "Novel MEMS L-Switching Matrix Optical Cross Connects Architecture: Design and Analysis - Optimal and Staircase Switching Algorithms," IEEE/OSA Journal of Lightwave Technology, vol. 23, no. 10, pp. 2877-2892, October 2005.
- J.T.W., Yeow, V.X.D., Yang, A., Chahwan, M.L. Gordon, B., Qi, I.A., Vitkin, B., Wilson, A.A., Goldenberg,Micromachined 2-D Scanner for 3-D Optical Coherence Tomography, Journal of Sensors and Actuators, A: Physical, Vol. 17, No. 2, pp. 331-340, Jan. 2005
- N. Sinha and John T.W. Yeow, Carbon Nanotubes for Biomedical Applications, IEEE Transactions on Nanobioscience, Vol. 4, No. 2, pp. 180-195, June 2005.
- T.W. Yeow, K.L.E. Law, A.A. Goldenberg, "SOI-Based 2D MEMS L-Switching Matrix for Optical Networking," IEEE Journal of Selected Topics in Quantum Electronics, vol.9, no. 2, pp.603-613, March-April 2003.
- T.W. Yeow, V. Askari, Z. Lu, A. Kapps, W. Fraser, A.A. Goldenberg, "An Expert System For Generation of Anti-G Control Schedule For Jet Fighter Pilots," International Journal of Expert Systems with Applications, pp. 257-266, vol. 22, no. 3, May 2002.
- T.W. Yeow, K.L.E. Law, A.A. Goldenberg, "MEMS Optical Switches," IEEE Communications magazine, pp. 158-163, vol.39 no.11, Nov. 2001.