Contacts

LinkedIn

​Research Gate

[YouTube Lecture] September 30, 2014 "An engineering prospective on Cancer'

PubMed

LinkedIn

ResearchGate

[CBB researcher story]

[YouTube] December 23, 2013 "Waterloo Engineering Research: Targeted Drug Delivery"

[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners

Research interests:

Research Interests:

• Design/discovery of potential therapeutics to target various diseases
• Understanding the structure and pharmacology of membrane proteins
• Development of in silico methods/tools for sequence, structure and functional analysis
• Inferring the structure-function evolution of proteins
• Protein engineering for biotechnology and pharmaceutical applications

[American Chemical Society] January 23, 2012 "Exploring Inhibitor Release Pathways in Histone Deacetylases Using Random Acceleration Molecular Dynamics Simulations"

[Wiley Online Library] July 27, 2013 "Ligand release mechanisms and channels in histone deacetylases"

[Royal Society of Chemistry] December 19, 2013 "A steered molecular dynamics mediated hit discovery for histone deacetylases"

[Nature Methods] May 8, 2017 "ModelFinder: fast model selection for accurate phylogenetic estimates"

[Royal Society of Chemistry] October 24, 2017 "Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction"

Research Interests:

• Low-dose, low-cost x-ray imaging system (e.g. tuberculosis screening)

• Circuit technology, Photon counting circuits for biomedical imaging

• Large area digital medical imaging

• Silicon Thin-film Applied Research

• Device physics

• Amorphous semiconductors and semiconductor devices

LinkedIn

ResearchGate

​Google Scholar

[Engineering News] November 12, 2018 "New X-ray technology to be tested on cancer patients"

[YouTube Lecture] September 30, 2014 "Bending the cost curve: Building a $1000 diagnostic X-ray imager for scalable and sustainable healthcare"

[Office of Research] "Paving the way for a digital X-ray and health-care revolution"

Research Interests:

• Integrative kidney physiology

• Biofluid dynamics

• Diabetes

• Hypertension

Google Scholar

March 29, 2018 "Canada 150 Research Chair joins Department of Applied Mathematics"

Research Interests:

Research interests:

[Science Mag] June 6, 2016 "This desert moss can water itself with fog"

[Nature] June 08, 2016 "How desert moss drinks from air"

[PNAS] June 22, 2017 "Cavitation onset caused by acceleration"

Research Interests:

• Biological fluid dynamics, fluid/structure interaction, vortex dynamics, diagnostic methods

• Energy harvesting

• Cardiovascular and mechanical blood flow models

• Human phonation, vocal fold modeling

• Stent modeling and design

• Biomimetic propulsors

LinkedIn

ResearchGate

Google Scholar

[CBB researcher story] January 8, 2013 "The Ability to be Heard Above the Crowd"

Research Interests

• Early Cancer Detection
• Eliminating Positive Surgical Margins
• Non-contact Biopsies for Endoscopy 
• Functional Brain Imaging 
• Early Detection and Understanding the Age-related Vision Loss Problems
• Wound Care
• Cardiovascular
• Machine learning/AI

[Linkedin]

[Google Scholar]

Research Interests:

Research Interests:

• Calcium channel analysis for target drug delivery for treatment of pain, arrhythmias, angina, and potential benefits in treatment of epilepsy and cancer.

• Structure, function and pharmacology of calcium channels and sodium channels

• Structure and function and analysis of NALCN cation channel  and anti-calcium channel toxins

• The Spafford Neurobiology Research Laboratory studies voltage-gated calcium channels, molecular physiology, biophysics, cell biology, protein biochemistry, fluorescence microscopy and tissue cultures.

LinkedIn

ResearchGate

​Google Scholar

[Science News] April 25, 2014 "Waterloo discovers a key regulator in the pacemakers of our brain and heart"

Research Interests:

• Biomedical image processing and analysis (prostate, breast, lung and dermatological cancer analysis, retinal photoreceptor and blood vessel analysis, musculoskeletal kinematic analysis

• Remote sensing data processing and analysis (sea ice, underwater object, oil spill analysis)

• Perceptual based video and image processing (noise reduction, compression, enhancement)

• Computer vision and pattern recognition

• Multimedia management systems

• 3D graphics and game development

• Cognitive radio networks

LinkedIn

Google Scholar

Canada Research Chair in Medical Imaging Systems [Canada Research Chair Profile]

[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners

[Waterloo News] [CBC News] [Gadgets] May 16, 2018, Co-authors discuss the use of aerobic fitness data from wearable tech to predict illness

[Waterloo News] May 15, 2018 "Researchers combine wearable technology and AI to predict the onset of health problems"

[Global Impact] [570 news] [Youtube] April 11, 2018 "How AI is helping doctors diagnose Cancer" 

[The Star] February 9, 2018 "How TheRedPin aims to take a swipe at the real estate industry"

[Waterloo News] June 7, 2017 "Artificial intelligence-driven imaging research makes diagnosing disease easier"

[Waterloo Stories] January 28, 2017 "Artificial intelligence and the Waterloo-Toronto tech supercluster"

[Waterloo Stories] May 20, 2016 "Breakthrough tech helps doctors more accurately diagnose cancer"

[CBB researcher story] January 9, 2013 "Improving Early Diagnosis to Save Lives"

[Waterloo Stories] January 9, 2013 "Making it harder for cancer to hide"

[YouTube Lecture] October 1, 2014 "Integrative systems for biomedical imaging and analysis"

Research Interests:

• MEMS/NEMS

• Nanodevices and carbon nanotube-based sensors for biomedical applications (early disease detection)

• Microassembly and micromirror devices for genetic microarray reading and tissue imaging

• Lab-on-a-chip designs

Canada Research Chair in Micro and NanoDevices [Canada Research Chair Profile]

Research Interests:

• Stem cells, nanofabrication and advancement of biomaterials in healthcare technologies to repair, replace or regenerate damaged tissue and organ structures

• Fabrication and application of nano-structure for biomedical applications in neural, vascular, and cornea tissue engineering

• ​Biomaterial approach to study ex-vivo pluripotent stem cell expansion

• Modulation of cell behavior with nanotopography

• Topography-regulation of stem cells lineage commitment and differentiation

• Differentiation of adult and pluripotent stem cells with nanotopography

Google Scholar

LinkedIn

Research Interests:

• Ultrasound imaging innovations: Complex flow imaging, High-performance beamforming platforms, Flow phantom design

• Therapeutic ultrasound discoveries: Sonoporation, Micro/nanobubble cavitation, Wave-matter interactions, Cellular dynamics studies

Google Scholar