Research Breakthrough - Todd Holyoak
Professor Todd Holyoak is an expert in the dynamic aspects of the enzyme structure-function relationship, or “conformational plasticity” in enzymology and how these dynamic aspects of enzyme structure can be altered/influenced to alter and enzyme function. Currently, the Holyoak lab is exploring the structure-function relationship in several diverse enzyme families with a current focus upon the GTP-dependent phosphoenolpyruvate carboxykinases (PEPCK) and the IgA1 protease family of bacterial proteins.