Murray Alzheimer Research and Education Program (MAREP)

Alzheimer's disease and related dementias are a world-wide phenomenon that ignores social class and national boundaries. As age is the greatest risk factor for the development of Alzheimer's disease, more and more individuals will be diagnosed with Alzheimer's disease and related dementias as the population ages.

At the present time there is no known cause or cure for Alzheimer's disease. As the search for an effective treatment continues, it is important that people who have Alzheimer's disease or a related dementia receive the best care possible and are provided with support and opportunities to live meaningful lives.

To implement effective approaches for care of people living with Alzheimer's disease and related dementias, contemporary research findings need to be brought to the attention of all partners in care including people with dementia, family members and friends, health care professionals, and so forth. The converse is true as well in that effective approaches to care need to be brought to the attention of researchers.

The Murray Alzheimer Research and Education Program (MAREP) is an innovative program that adopts a partnership approach and integrates research and educational activities in an effort to improve dementia care practices in Canada and around the world. Although MAREP's research projects are funded by research grants, all of its knowledge translation activities are funded through donations and charitable gifts from individuals and groups: find out how you can support our programs.

More information is available for people living with dementia, care partners, and anyone else affected by dementia in our Innovations Newsletter, published three times per year, the Dementia Weekly News Service, our blog, and the educational tools and training and workshops we offer. 

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  1. June 18, 2018Spread of Aggregated Protein in Alzheimer's Disease Linked to Exosomes

    Although traditionally thought as the waste disposal units of the cell, exosomes have a much more complex relationship with the processing of information between cells as well. Researchers out of Linköping University have found that exosomes are spreading amyloid proteins to unaffected neurons in patients with Alzheimer’s disease. The spread of the disease has alluded researchers, as it was assumed that it was passed through proximity. Absorption of exosomes in unaffected neurons offers the answer to why spread of the disease can be observed in other parts of the brain.

  2. June 18, 2018High Blood Pressure Associated with Dementia Risk

    Another reason to watch your blood pressure has been looked at by researchers out of the Regional Excellence Hypertension Center of the Italian Society of Hypertension in the Department of Angiocardioneurology and Translational Medicine of the I.R.C.C.S, Neuromed. Researchers asked people ages 40 to 65 with no prior symptoms or diagnosis of dementia to screen for their hypertensive status and organ damage. An MRI was utilized to determine the presence of microstructural damage in white matter of participants in relation to hypertensive status.

  3. June 18, 2018Another Disappointment as AstraZeneca and Eli Lilly Pharmaceutical Companies Discontinue Trails for Alzheimer's Drug

    The fight to find a cure has hit another roadblock this week as pharmaceutical companies AstraZeneca and Eli Lilly announced that they were discontinuing their phase three trials for an experimental drug. People with early-stage Alzheimer’s disease were given lanabecestat at 20mg, 50 mg, or a placebo to assess the drug’s effects. Lanabecestat is an experimental BACE inhibitor that is being called off after the data monitoring committee saw that the drug was unlikely to meet primary endpoints.

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  1. July 25, 2017Canada's National Dementia StrategyMary Beth Wighton Quote

    Last month, Bill C-233, an Act respecting a national strategy for Alzheimer’s disease and other dementias, sponsored by the Honourable Rob Nicholson and Rob Oliphant, was passed. Canada will be the 30th country out of 194 members of the World Health Organization to implement a national dementia plan.

  2. June 6, 2017To the Nurse Who May Care for Me TodayBlog quote

    Hi I am your assignment for today.

    I know I am just one of many but I ask you to please take the time to know me. You see I once was also a nurse. That really doesn't matter as I am a human being. I come with an education and feeling. I am also a wife a mother, a grandmother and more. Please take the time to read my chart as you can gain much knowledge about me before you ever meet me. In it you will find my medical history, this may give you a glimpse of what to expect from me. It will tell you what is being treated now. Know full well that, that may not be my only problem.  

  3. May 2, 2017Ontario Dementia Advisory Group e-newsletter, April 2017

    A Letter from the Chair

    APRIL 2017

    Hello, ODAG Members, Friends, and Supporters.

    The last two months have been very interesting for people living with dementia. It is a time of policy changes, budget allocations and the broadening of the Council of Canadians with Disabilities to formally include people living with dementia.

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