A research team including Dr. Brian Ingalls, professor of applied mathematics, is developing a novel tool to treat cancer by engineering hungry bacteria to literally eat tumours from the inside out.
“Bacteria spores enter the tumour, finding an environment where there are lots of nutrients and no oxygen, which this organism prefers, and so it starts eating those nutrients and growing in size,” said Dr. Marc Aucoin, a chemical engineering professor at Waterloo. “So, we are now colonizing that central space, and the bacterium is essentially ridding the body of the tumour.”
Key to the approach is a bacterium called Clostridium sporogenes, which is commonly found in soil and can only grow in environments with absolutely no oxygen.
Read the full story from Waterloo News to learn more.